ID V5BSW5_TRYCR Unreviewed; 297 AA.
AC V5BSW5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Cleavage and polyadenylation specificity factor subunit 2 {ECO:0000256|RuleBase:RU365006};
DE AltName: Full=Cleavage and polyadenylation specificity factor 100 kDa subunit {ECO:0000256|RuleBase:RU365006};
GN ORFNames=TCDM_02045 {ECO:0000313|EMBL:ESS69287.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS69287.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS69287.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS69287.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU365006}.
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. RNA-
CC metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
CC {ECO:0000256|RuleBase:RU365006}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS69287.1}.
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DR EMBL; AYLP01000013; ESS69287.1; -; Genomic_DNA.
DR AlphaFoldDB; V5BSW5; -.
DR EnsemblProtists; ESS69287; ESS69287; TCDM_02045.
DR VEuPathDB; TriTrypDB:TCDM_02045; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006378; P:mRNA polyadenylation; IEA:InterPro.
DR InterPro; IPR027075; CPSF2.
DR InterPro; IPR025069; Cpsf2_C.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR45922; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2; 1.
DR PANTHER; PTHR45922:SF1; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2; 1.
DR Pfam; PF13299; CPSF100_C; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|RuleBase:RU365006};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365006};
KW Reference proteome {ECO:0000313|Proteomes:UP000017861};
KW RNA-binding {ECO:0000256|RuleBase:RU365006}.
FT DOMAIN 129..293
FT /note="Cleavage and polyadenylation specificity factor 2 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13299"
SQ SEQUENCE 297 AA; 33561 MW; DC3576E2A65C704E CRC64;
MQFLMRRKAP ARIYSDEGPE GIQMHNDAQA EANIPSKTFV NTAMVRKNSR VFMTDLSGFA
DAAIMRSLLK SRFSFAKKIV LIRGTVDDHR ALYQFCRSEK VMKCGENVFF PRTQRTHLEL
ATHVYSYMVQ LDPTLANALP SALRRVKESR SSGFWDVGWV DGALESSFVS LTPEDDERQS
VKRLRAEGNG GEIKDGVFTL VPLFGERAQQ CARERELRGM QRGLFYVGDV DLHRLREVAR
NEMGLRGEFH KNAPMLVFDA GLCVRKSANG NFSLSSMISP SVFALRKTVY GQFSQTL
//
