ID   V5BZN2_9GAMM            Unreviewed;       510 AA.
AC   V5BZN2;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Histidine ammonia-lyase HutH {ECO:0000313|EMBL:ESS73284.1};
DE            EC=4.3.1.3 {ECO:0000313|EMBL:ESS73284.1};
GN   Name=hutH {ECO:0000313|EMBL:ESS73284.1};
GN   ORFNames=MGMO_27c00270 {ECO:0000313|EMBL:ESS73284.1};
OS   Methyloglobulus morosus KoM1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methyloglobulus.
OX   NCBI_TaxID=1116472 {ECO:0000313|EMBL:ESS73284.1, ECO:0000313|Proteomes:UP000017842};
RN   [1] {ECO:0000313|EMBL:ESS73284.1, ECO:0000313|Proteomes:UP000017842}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KoM1 {ECO:0000313|EMBL:ESS73284.1,
RC   ECO:0000313|Proteomes:UP000017842};
RX   PubMed=24356841;
RA   Poehlein A., Deutzmann J.S., Daniel R., Simeonova D.D.;
RT   "Draft Genome Sequence of the Methanotrophic Gammaproteobacterium
RT   Methyloglobulus morosus DSM 22980 Strain KoM1.";
RL   Genome Announc. 1:e01078-13(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESS73284.1}.
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DR   EMBL; AYLO01000027; ESS73284.1; -; Genomic_DNA.
DR   AlphaFoldDB; V5BZN2; -.
DR   STRING; 1116472.MGMO_27c00270; -.
DR   PATRIC; fig|1116472.3.peg.887; -.
DR   eggNOG; COG2986; Bacteria.
DR   OrthoDB; 9806955at2; -.
DR   Proteomes; UP000017842; Unassembled WGS sequence.
DR   GO; GO:0004397; F:histidine ammonia-lyase activity; IEA:UniProtKB-EC.
DR   CDD; cd00332; PAL-HAL; 1.
DR   Gene3D; 1.20.200.10; Fumarase/aspartase (Central domain); 1.
DR   Gene3D; 1.10.275.10; Fumarase/aspartase (N-terminal domain); 1.
DR   InterPro; IPR001106; Aromatic_Lyase.
DR   InterPro; IPR024083; Fumarase/histidase_N.
DR   InterPro; IPR008948; L-Aspartase-like.
DR   InterPro; IPR022313; Phe/His_NH3-lyase_AS.
DR   PANTHER; PTHR10362; HISTIDINE AMMONIA-LYASE; 1.
DR   PANTHER; PTHR10362:SF7; HISTIDINE AMMONIA-LYASE; 1.
DR   Pfam; PF00221; Lyase_aromatic; 1.
DR   SUPFAM; SSF48557; L-aspartase-like; 1.
DR   PROSITE; PS00488; PAL_HISTIDASE; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:ESS73284.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017842}.
SQ   SEQUENCE   510 AA;  55874 MW;  9CDA51325F3323A3 CRC64;
     MTENTVLVNG DRLTIEDICH LANQTKALQL SDAVNFRDRI DKGALFVNKL LREEGVVYGI
     TTGYGDSCTV PIPLEYVADL PRNLYTFHGC GLGTHFDRVQ TRAIMAVRIN SLAQGFSGVR
     YQLLLQISQL LKHDILPLIP QEGSVGASGD LTPLSYLAAV VAGEREVWYQ GQIQSAETVF
     NALTIAPLKL NPKEGLAIMN GTAVMTALAC LAYQRAAYLS QLSTRITSLV SVALLGNAGH
     FDESLFSVKP HEGQIKVARR IREDLSVVGQ ASRNDARLQD RYSLRCAPHV IGVLEDALPW
     FRQFIENELN SANDNPIIDA EHERVLHGGH FYGGHIAFAM DSLKTVVANL ADLIDRQMAQ
     LVDPKFNHGL PANLSGAKGE QAMLNHGFKA VQIAVSAWTA EALKLTMPAS VFSRSTECHN
     QDKVSMGTIA ARDCIRVLEL TEQVAAAVLI AAVQAVELRS EGQPLSANLN MTLSQVREHV
     PFLEADRALE QALRLCLQLI RDQHWSLYGP
//