ID V5CJM0_TRYCR Unreviewed; 555 AA.
AC V5CJM0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Trans-sialidase {ECO:0000313|EMBL:ESS55536.1};
GN ORFNames=TCDM_12983 {ECO:0000313|EMBL:ESS55536.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS55536.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS55536.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS55536.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS55536.1}.
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DR EMBL; AYLP01000783; ESS55536.1; -; Genomic_DNA.
DR AlphaFoldDB; V5CJM0; -.
DR EnsemblProtists; ESS55536; ESS55536; TCDM_12983.
DR VEuPathDB; TriTrypDB:TCDM_12983; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13859; BNR_3; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017861};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..354
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT REGION 62..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 60339 MW; B32B175E616CA82C CRC64;
MNGDVFAVAE ALCTGKKDTV EGGFTGIASE LLELTGEQKE EELDKSKLKT QVLDRCPFEG
GNCPSQTAAE EGGSQSETKV HVSRPTTVVD GSDIYMLAGN YSNKGASEDQ AGDWGILLVS
GNVSTVDGKK RIYWNDTYGL PSAFFEKQHK SLTQLTSGGG SGIKMNDGTL VFPVEATKKE
TNNEEEVKTK TVSLIIHSLK DIASWKLSKG MSADGCGDLS VVEWEKGNLM MMTACDDGRR
RVYESGDKGD SWTEALGTLS RVWGNKKGET VEIVGSGFIT AKIDNRDVML VTLPVYSSKD
GEGNQKSELH LWLTDNTHIV DIGSVSEKED DVTASSLLYK SGNDNNEKLI ALYEKKKNGN
EDTSLGMASA LLTAQLQRVK KVLKTWKEVD ERVSKLCPTE NVGKDRSPNT ACNADVKITD
GLVGFLSDNF SGDTWKDEYL GVNATVNNND DRATKTSDGV TFQGAWAEWP VGKQGENQLY
HFANYNFTLV ATVSIDGVPT EGNIPVMGVK MNDDEKEKNL LSCHTTAKRS GSCYVVAKLL
RSSAALWGKR EQITL
//
