ID V5EMP8_KALBG Unreviewed; 969 AA.
AC V5EMP8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Nucleoside phosphatase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PSEUBRA_SCAF3g03902 {ECO:0000313|EMBL:EST06400.1};
OS Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Kalmanozyma.
OX NCBI_TaxID=1365824 {ECO:0000313|EMBL:EST06400.1, ECO:0000313|Proteomes:UP000019377};
RN [1] {ECO:0000313|Proteomes:UP000019377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GHG001 {ECO:0000313|Proteomes:UP000019377};
RX PubMed=24356824; DOI=10.1128/genomea.00920-13;
RA Oliveira J.V.D.C., dos Santos R.A.C., Borges T.A., Riano-Pachon D.M.,
RA Goldman G.H.;
RT "Draft genome sequence of Pseudozyma brasiliensis sp. nov. strain GHG001, a
RT high producer of endo-1,4-xylanase isolated from an insect pest of
RT sugarcane.";
RL Genome Announc. 1:E0092013-E0092013(2013).
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283}.
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DR EMBL; KI545873; EST06400.1; -; Genomic_DNA.
DR RefSeq; XP_016291389.1; XM_016437839.1.
DR AlphaFoldDB; V5EMP8; -.
DR STRING; 1365824.V5EMP8; -.
DR GeneID; 27420517; -.
DR eggNOG; KOG1386; Eukaryota.
DR HOGENOM; CLU_304867_0_0_1; -.
DR OMA; IPRIVDH; -.
DR OrthoDB; 180318at2759; -.
DR Proteomes; UP000019377; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IEA:UniProt.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF121; NUCLEOSIDE-DIPHOSPHATASE MIG-23; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000019377};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 627..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 726..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 780..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 935..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 939..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 249
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 293..297
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 969 AA; 103635 MW; FF76E55200D15C48 CRC64;
MSYSIQGSSS QPYGAYTFNT PVKRRQRAQV LQTSQQQQRR SSQSNHPSRR ENIADAYTWN
AAAKTNKPKP GSKLNESPLK DAVPGAAQLD APASWLEGRK YAVLIDAGSS GSRMQVYSWK
DPKLERALRA SKGLDAKVLP KVEKGTWENS GVDWSHKVEP GLSSFGDRPA EVGNYLKGLL
DHAEKIVPPS AWADTPIYVM ATAGMRLLPD QQRTSVLFET CRYIREHTRF SLDGGGCEEH
VQVISGEEEG LLGWISVNYL MDGFHIRGKK ASLDGETDIM EGKSTFGFLD MGGASTQIAF
EPSKKALQGD GAAAEADLTT VPLRMLDGTE VSHKVFVTTF LGYGTNKARD RYIDLLQSGA
VKAHETSHTL SDPCLPNGLQ LANVNVGGKT DLSLMGAGNF TACLESMHPL LDKEAVCDKP
PCLFHGVHVP KIDFSVNHFI GVSEYWFSSH DVFGLGGVYD FVDFQKAAEG FCEKPWADLK
KHLDAGDLFG PEVQLSRLQT QCFKAAWMVT VLHEGIGIPR IVDHKGAGDG TDHADQANDK
GEQKNLFQSV NDINGFSVSW TLGKAVLEAS RDIPPAPGSL PSPFDELSKT NPKLGKWDPF
RPKWPTTGEG SAFPPALGET ARHVSPISLI IMVAAFLILL LTCVCTRGRG PRASRRRAAM
KDMLPPPLGT LGGFCSSKRT SRGDYVLANM EEAAGDASKS GFWSKLGKRA EFKSYSPTME
AEFGFNAEGS SEESSSGSSG SAGRGGSRTA SRKRANAGVV GALGWPARRL AFALTSTFPS
LSSRRKPRSK KRDSSLPISR DGAGSDGGLG HSARIASRRG ATTPTMVRIS RPASPTFTGM
TTGAAISRPA SRTSSRAPTP VLGHRLTSAT LSTRSGAITP GGSVMASSVG PAGILSPSGP
SSPLGERHAR PGLFSASLSR VHSITDMTTI ESGLLVAPAT RTPSRQGSPS ASGLSPMSEL
RREDGEIDV
//
