ID   V5ENL6_KALBG            Unreviewed;       689 AA.
AC   V5ENL6;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25 {ECO:0000256|ARBA:ARBA00015422, ECO:0000256|RuleBase:RU365070};
DE            Short=U3 snoRNA-associated protein 25 {ECO:0000256|RuleBase:RU365070};
GN   ORFNames=PSEUBRA_SCAF3g04173 {ECO:0000313|EMBL:EST06675.1};
OS   Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Kalmanozyma.
OX   NCBI_TaxID=1365824 {ECO:0000313|EMBL:EST06675.1, ECO:0000313|Proteomes:UP000019377};
RN   [1] {ECO:0000313|Proteomes:UP000019377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GHG001 {ECO:0000313|Proteomes:UP000019377};
RX   PubMed=24356824; DOI=10.1128/genomea.00920-13;
RA   Oliveira J.V.D.C., dos Santos R.A.C., Borges T.A., Riano-Pachon D.M.,
RA   Goldman G.H.;
RT   "Draft genome sequence of Pseudozyma brasiliensis sp. nov. strain GHG001, a
RT   high producer of endo-1,4-xylanase isolated from an insect pest of
RT   sugarcane.";
RL   Genome Announc. 1:E0092013-E0092013(2013).
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC       processing, specifically at sites A0, A1, and A2.
CC       {ECO:0000256|ARBA:ARBA00002883, ECO:0000256|RuleBase:RU365070}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3.
CC       {ECO:0000256|RuleBase:RU365070}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU365070}.
CC   -!- SIMILARITY: Belongs to the UTP25 family.
CC       {ECO:0000256|ARBA:ARBA00009223, ECO:0000256|RuleBase:RU365070}.
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DR   EMBL; KI545873; EST06675.1; -; Genomic_DNA.
DR   RefSeq; XP_016291664.1; XM_016438110.1.
DR   AlphaFoldDB; V5ENL6; -.
DR   STRING; 1365824.V5ENL6; -.
DR   GeneID; 27420788; -.
DR   eggNOG; KOG2340; Eukaryota.
DR   HOGENOM; CLU_018705_3_0_1; -.
DR   OMA; KYFRQTI; -.
DR   OrthoDB; 5473087at2759; -.
DR   Proteomes; UP000019377; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; ORF PROTEIN-RELATED; 1.
DR   PANTHER; PTHR12933:SF0; U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG; 1.
DR   Pfam; PF06862; UTP25; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365070};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019377};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW   ECO:0000256|RuleBase:RU365070};
KW   Ribosome biogenesis {ECO:0000256|RuleBase:RU365070};
KW   rRNA processing {ECO:0000256|RuleBase:RU365070}.
FT   REGION          18..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        39..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   689 AA;  76663 MW;  8CDBA76FD3F30FDE CRC64;
     MDPTLKLLTL INVSAAKPGK RQRSSNLTHY DKITRKAVAA QQATASTSKA ALSSTPSPSK
     RAKNGAAPVA STTISQNGLE LVGEVSDDDE EDFDAASSSA PKKQQKKSQI TAFDAHFGSD
     GPHAQAIAKL PESTTSLTWS TSRSTLPSFS TQLIVSSPSL PEFDSQQYSG QPQVKVLDAF
     NAFTAKHFSS PTPLHKALAT TLGSYADFCD ANVALRDRAQ YRQVLAMHAM SHVAKTRRRV
     LKNNEKLAKL AASGASDADT DLDLRDQGFT RPKVLVLLPF RNSALEWVDL LTKFSLCSQV
     DNKSRFAKEY NLPEGAIDKL ADASVAAKYP EDHIANFAGN IDDSFKLGLK VTRKSLKLFS
     GFYDSDVIVA SPLGLRLGME KDKGDSDFLS SIEMVIVDQT DVISMQNWEH LEYVFDKLNH
     IPRQSRDTDF SRVKQFYLDN RAGMFRQTIM LSAHDFPALR SVYNHTLQNV AGKIRTVAPT
     PESEAEMSKV VSGVRQTFTR FEAANPHSEP DLRFAHFTTK TLAQLSKSAV SSSHTLILVP
     SYFDFVRLDA FLREHNEKRK PGETANLSYT SISEYSTPKD IRRAREAFAS GKKRFLLLTE
     RAHFYRRFKI RGTKTVVFYQ VPQNARYFSE VLEFPFLNKD WGEEEEVDAN EVASYVVYSK
     YDLIGLEKVV GTEQAKAMVA GDKATWKFV
//