ID   V5EU77_KALBG            Unreviewed;       714 AA.
AC   V5EU77;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300};
GN   ORFNames=PSEUBRA_SCAF5g02481 {ECO:0000313|EMBL:EST05624.1};
OS   Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Kalmanozyma.
OX   NCBI_TaxID=1365824 {ECO:0000313|EMBL:EST05624.1, ECO:0000313|Proteomes:UP000019377};
RN   [1] {ECO:0000313|Proteomes:UP000019377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GHG001 {ECO:0000313|Proteomes:UP000019377};
RX   PubMed=24356824; DOI=10.1128/genomea.00920-13;
RA   Oliveira J.V.D.C., dos Santos R.A.C., Borges T.A., Riano-Pachon D.M.,
RA   Goldman G.H.;
RT   "Draft genome sequence of Pseudozyma brasiliensis sp. nov. strain GHG001, a
RT   high producer of endo-1,4-xylanase isolated from an insect pest of
RT   sugarcane.";
RL   Genome Announc. 1:E0092013-E0092013(2013).
CC   -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also
CC       known as the alpha DNA polymerase-primase complex) which plays an
CC       essential role in the initiation of DNA synthesis.
CC       {ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC       {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}.
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DR   EMBL; KI545891; EST05624.1; -; Genomic_DNA.
DR   RefSeq; XP_016290613.1; XM_016438766.1.
DR   AlphaFoldDB; V5EU77; -.
DR   STRING; 1365824.V5EU77; -.
DR   GeneID; 27421462; -.
DR   eggNOG; KOG1625; Eukaryota.
DR   HOGENOM; CLU_014923_2_0_1; -.
DR   OMA; PFLDIEH; -.
DR   OrthoDB; 49016at2759; -.
DR   Proteomes; UP000019377; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.21.60; -; 2.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR016722; DNA_pol_alpha_bsu.
DR   InterPro; IPR013627; Pol_alpha_B_N.
DR   PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR   PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
DR   Pfam; PF08418; Pol_alpha_B_N; 1.
DR   PIRSF; PIRSF018300; DNA_pol_alph_2; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW   ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019377}.
FT   DOMAIN          23..274
FT                   /note="DNA polymerase alpha subunit B N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08418"
FT   DOMAIN          415..652
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
FT   REGION          138..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   714 AA;  76022 MW;  EF67D236673EA02A CRC64;
     MVASDLTVRL ADHFGPYIAS DPSLLTETTS ICTHYRITPE DLFYKWEAFA INNSLPKSEP
     LTLDHARELR KIIATAVNSA AASAAAGAGD ATPLKPSNAL NRGKVAGDLG QMLGIKSTPL
     KPQQGNAFQT PVRAASSSFS PFGGPGATPA TASAYKPSGI RDSDVHMSDV DSPLRPSPAA
     PSKSVHAPYT ILESLNEHIP LVPSGSHLLP AGRKSRVSLA MATDPKAWNY RYMFEKKDER
     SSVLDDRIDQ FAALLRETYS LPSDEELGDP SLPSQEPIWV VGRICPALPA PESSAGHTLR
     GKREEAFGLP KLAETGIVLE SSRMMGSGNR TPLVFAKGCV VRHTPQDPGT GGAATTLSLF
     PGQIVLCRGI NAGADKFSVS EICFPPPLPL AVHTAGEAID HSYSPGKLNG AALNVVLASG
     PFTSESDLDF APWHRLMDAL EAGGLPSDAT SDSRRGVPDT LVLTGPFLSA QHPLLPFATE
     LPSDIFARHI STRLTALLAK YPGTMVVLIP STQDILNIHS AYPQPSFGKE DATGPMGLPK
     ARVRCLPNPS VFYVNELVVG VTSEDALGDL KGEEMVTRIE ASPTPAKVIG ESVASKNKET
     NTRWSRSILS QRSFYPLYPP PTAAGLAYDT SHSHLLGFPA VTPDLLVLPS RKLAKPFLRV
     VSSATVVQPG SVAKGTVVCV QVDPLPRAEL QGKDEMESIN ARLYDRARVD VVAI
//