ID V5FMJ5_BYSSN Unreviewed; 819 AA.
AC V5FMJ5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=PVAR5_7918 {ECO:0000313|EMBL:GAD99209.1};
OS Byssochlamys spectabilis (strain No. 5 / NBRC 109023) (Paecilomyces
OS variotii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX NCBI_TaxID=1356009 {ECO:0000313|EMBL:GAD99209.1, ECO:0000313|Proteomes:UP000018001};
RN [1] {ECO:0000313|Proteomes:UP000018001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=No. 5 / NBRC 109023 {ECO:0000313|Proteomes:UP000018001};
RX PubMed=24407650; DOI=10.1128/genomeA.01162-13;
RA Oka T., Ekino K., Fukuda K., Nomura Y.;
RT "Draft genome sequence of the formaldehyde-resistant fungus Byssochlamys
RT spectabilis No. 5 (anamorph Paecilomyces variotii No. 5) (NBRC109023).";
RL Genome Announc. 2:E0116213-E0116213(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD99209.1}.
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DR EMBL; BAUL01000285; GAD99209.1; -; Genomic_DNA.
DR AlphaFoldDB; V5FMJ5; -.
DR eggNOG; KOG0922; Eukaryota.
DR HOGENOM; CLU_001832_5_11_1; -.
DR InParanoid; V5FMJ5; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000018001; Unassembled WGS sequence.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000018001}.
FT DOMAIN 139..331
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 386..562
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 819 AA; 90648 MW; 266BEFFAD8BA6225 CRC64;
MPEKVHTRFE DSDDDAGKAT VRPQKKEQAA AADPVVTEPR EKKNKKRKRE ETAEVKPNTQ
RVVIRDGEKP RAVSPAQEGE QKRNVKEASN GFNSQKKHQS KDQKMIRQGK PSSSLREKAR
ALYEIRKKLP IFPHADEIRQ RLKKDDVMLL VGETGSGKST QIPQFLVDES WCRPKTVKVT
AEDGKQKDVN VGGCIAITQP RRVAAISLAR RVADEMGTPL GSSSPGSRVG YSVRFDTSTS
PSTKVKYLTE GMLLQEMLHD PWLTKYSAVL VDEVHERGVN VDLVLGFLRN IVSGKKEGRG
GIPLKVLAMS ATADMESLLS FFQEGFDNAQ RAETDSTNAS DSAPNDQDSK ADEKQRQVAV
CHIKGRQFPV KTIYTPDPVH DFVDAALKVI FQIHCKEPMP GDILVFLTGQ ETVEALEYLV
NDYAIGMDPA LPKVQVLPLF AALPQAAQQR VFQPAPPRTR KIILATNIAE TSVTISGIRF
VVDCGKAKMK QFRTRLGLDS LLVKPISKSA AIQRKGRAGR EAPGQCYRLY TEKDYLALQE
TNTPEILRCD LSQAILTMKA RGVDDIVGFP FLTRPSREAL EKALLQLFNI QALEESGKIS
SIGLQIAKLP LTAPLGRVLL AAAQNGPNCL LDVIDIISAL SVENIFLNTT SEEKKEEAEK
ARRDLFRREG DHLTMLATVQ AYAAENTDRK AWAERHMVSH RAMQSVMDVR KQLTTQCRQA
KLLPDANACA SLANNQPDPV LILKSFLTGF ATNTARIIPD GSYRTIVGNQ TVAIHPSSVL
FGKKVEAIMY NEFVFTNRSY ARGVSAVQMD WVGEVLAGQ
//
