ID V5G201_BYSSN Unreviewed; 399 AA.
AC V5G201;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Cystathionine gamma-synthase {ECO:0000313|EMBL:GAD98403.1};
GN ORFNames=PVAR5_7095 {ECO:0000313|EMBL:GAD98403.1};
OS Byssochlamys spectabilis (strain No. 5 / NBRC 109023) (Paecilomyces
OS variotii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX NCBI_TaxID=1356009 {ECO:0000313|EMBL:GAD98403.1, ECO:0000313|Proteomes:UP000018001};
RN [1] {ECO:0000313|Proteomes:UP000018001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=No. 5 / NBRC 109023 {ECO:0000313|Proteomes:UP000018001};
RX PubMed=24407650; DOI=10.1128/genomeA.01162-13;
RA Oka T., Ekino K., Fukuda K., Nomura Y.;
RT "Draft genome sequence of the formaldehyde-resistant fungus Byssochlamys
RT spectabilis No. 5 (anamorph Paecilomyces variotii No. 5) (NBRC109023).";
RL Genome Announc. 2:E0116213-E0116213(2014).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD98403.1}.
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DR EMBL; BAUL01000243; GAD98403.1; -; Genomic_DNA.
DR AlphaFoldDB; V5G201; -.
DR eggNOG; KOG0053; Eukaryota.
DR HOGENOM; CLU_018986_3_0_1; -.
DR InParanoid; V5G201; -.
DR OrthoDB; 5482552at2759; -.
DR Proteomes; UP000018001; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF35; CYSTATHIONINE GAMMA-SYNTHASE (AFU_ORTHOLOGUE AFUA_7G01590); 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000018001}.
FT MOD_RES 205
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 399 AA; 44170 MW; 9B2C8DF3D4F6E4F4 CRC64;
MANHENARPA TLALHADDAL NNVTDVAPPL HLSTTYRYSD NPEDLVPWAD ATDHHIDPKS
HIYSRFTSPN GTRFETILSA LTNGHALTYS SGLSALHAAL VLFNPRHISI GQNYHGCFGV
IGLMSRLTGL QQLDIDCPAE QLEEGDVVLL ETPINPHGVA SNIEEYAKKA HSRGAFLIVD
STFAPPALQD PFLWGADLVM HSGSKYFGGH SDVLCGVLVT QKKAWYDKLL GDRLYLGSVM
GNMESWLGVR SLRTLEVRVQ RQSQNAEKLV AWLDNAMQAS DPLAGSDEAV AKAALHKVYH
ASLQKEDMSW LRKQMPNGYG PVFSIILKEE EFARKVPTKL AFFHHATSLG GVESLIEWRT
MTDAKVDRRL LRISVGLENW EDLKNDLVAA FRAVLQEKA
//
