ID V5G7X6_BYSSN Unreviewed; 445 AA.
AC V5G7X6;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Oleate delta-12 desaturase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PVAR5_6806 {ECO:0000313|EMBL:GAD98116.1};
OS Byssochlamys spectabilis (strain No. 5 / NBRC 109023) (Paecilomyces
OS variotii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Thermoascaceae; Paecilomyces.
OX NCBI_TaxID=1356009 {ECO:0000313|EMBL:GAD98116.1, ECO:0000313|Proteomes:UP000018001};
RN [1] {ECO:0000313|Proteomes:UP000018001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=No. 5 / NBRC 109023 {ECO:0000313|Proteomes:UP000018001};
RX PubMed=24407650; DOI=10.1128/genomeA.01162-13;
RA Oka T., Ekino K., Fukuda K., Nomura Y.;
RT "Draft genome sequence of the formaldehyde-resistant fungus Byssochlamys
RT spectabilis No. 5 (anamorph Paecilomyces variotii No. 5) (NBRC109023).";
RL Genome Announc. 2:E0116213-E0116213(2014).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD98116.1}.
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DR EMBL; BAUL01000229; GAD98116.1; -; Genomic_DNA.
DR AlphaFoldDB; V5G7X6; -.
DR eggNOG; ENOG502QQNB; Eukaryota.
DR HOGENOM; CLU_033094_0_0_1; -.
DR InParanoid; V5G7X6; -.
DR OrthoDB; 4215at2759; -.
DR Proteomes; UP000018001; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProt.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF35; OMEGA-3 FATTY ACID DESATURASE FAT-1; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018001};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..62
FT /note="Fatty acid desaturase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11960"
FT DOMAIN 83..366
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 445 AA; 50580 MW; 0BD06D98356B4FDA CRC64;
MSLGPYSSAS RGHVDLYGNV FEVPDFTMKQ IYDAIPPHCF RPSTLRSMSY VVRDYALLGG
LAWLVYTYTP LLPSIWLRAT SYALYTVIAG MIMTGIWILA HECGHGAFSK SKSLNNTVGF
ILHSSLLVPY YSWKISHSHH HKSTGDLQRD TVFVPHSREY WVKTTLGKEV DPHSISAAEV
TEDAPIVTLW HCILHQVFGW PLYMLDNLSG QKGVHGFPQH SHYWFGSDSG IYKESELFSV
FLSDIGILAT CGLLYLAVRV SDLWTVLIFY GIPYLWLNHW IVAITYLQHT DGTLPHFAHS
QWTFARGAAA TIDRSFKLGF FDIDMYLFHG IVGTHVLHHL VSSIPFYHAY EATEAVKKVM
GKHYHSDKET PLMTALFRMQ RDCQFVEESS GMDGSGVYMF RNLHGRGTKP RDLVGGQRLS
SWEGHVPPPK GKEDWNWRDL ISSVW
//
