ID V5GL41_KALBG Unreviewed; 437 AA.
AC V5GL41;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=2-dehydropantoate 2-reductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PSEUBRA_SCAF3g04182 {ECO:0000313|EMBL:EST06672.1};
OS Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Kalmanozyma.
OX NCBI_TaxID=1365824 {ECO:0000313|EMBL:EST06672.1, ECO:0000313|Proteomes:UP000019377};
RN [1] {ECO:0000313|Proteomes:UP000019377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GHG001 {ECO:0000313|Proteomes:UP000019377};
RX PubMed=24356824; DOI=10.1128/genomea.00920-13;
RA Oliveira J.V.D.C., dos Santos R.A.C., Borges T.A., Riano-Pachon D.M.,
RA Goldman G.H.;
RT "Draft genome sequence of Pseudozyma brasiliensis sp. nov. strain GHG001, a
RT high producer of endo-1,4-xylanase isolated from an insect pest of
RT sugarcane.";
RL Genome Announc. 1:E0092013-E0092013(2013).
CC -!- SIMILARITY: Belongs to the ketopantoate reductase family.
CC {ECO:0000256|ARBA:ARBA00007870}.
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DR EMBL; KI545873; EST06672.1; -; Genomic_DNA.
DR RefSeq; XP_016291661.1; XM_016438119.1.
DR AlphaFoldDB; V5GL41; -.
DR STRING; 1365824.V5GL41; -.
DR eggNOG; ENOG502QPT5; Eukaryota.
DR HOGENOM; CLU_031468_10_2_1; -.
DR OMA; RKEPFQV; -.
DR OrthoDB; 1354873at2759; -.
DR Proteomes; UP000019377; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR013752; KPA_reductase.
DR InterPro; IPR013332; KPR_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43765; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR PANTHER; PTHR43765:SF2; 2-DEHYDROPANTOATE 2-REDUCTASE-RELATED; 1.
DR Pfam; PF02558; ApbA; 1.
DR Pfam; PF08546; ApbA_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019377}.
FT DOMAIN 3..164
FT /note="Ketopantoate reductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02558"
FT DOMAIN 267..427
FT /note="Ketopantoate reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08546"
SQ SEQUENCE 437 AA; 47529 MW; 12E1420476DE30C1 CRC64;
MRYHVLGVGS IGSLIAFHLK RSVKLQRQLL QPGPSSSKSR RELLLSNLSN KAPPQRQGTI
VSSLSHPPYI QSELPDPLQT LIITTKCDTT LSALESIRHR IHPWSTIVLL QNGMGVLDTL
FDTFFKDPES RPNFILASTT HGCWRKGPLD IMHASPGALH FGIVPSGRAG SEGFEAEKVP
FGHTIATVKG GLLPTIGSAA SKKARGWERF APDADADPQK ELDPNSLSSK LSIGSIPDQP
NLRTLRATVA GLLSLPLNVE WEPIREFQLR ALRKVVINAC INPLTALADC KNGDLFGNPA
AMDAMWSVCL EAGMVLEAQV REHLSSSSDA SKRKSTAGLS TEDLLILSTE TGEPMLHPSL
TPQALFQEAQ RVARMTAANW SSMHADLKKR RGSTEIDYIN GYISALGRGY NIDTTANDLL
TNMIKLKTSK VTGSGRF
//
