ID   V5GQG5_KALBG            Unreviewed;      1600 AA.
AC   V5GQG5;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=GTPase activating protein {ECO:0000313|EMBL:EST08177.1};
GN   ORFNames=PSEUBRA_SCAF18g04735 {ECO:0000313|EMBL:EST08177.1};
OS   Kalmanozyma brasiliensis (strain GHG001) (Yeast) (Pseudozyma brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Kalmanozyma.
OX   NCBI_TaxID=1365824 {ECO:0000313|EMBL:EST08177.1, ECO:0000313|Proteomes:UP000019377};
RN   [1] {ECO:0000313|Proteomes:UP000019377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GHG001 {ECO:0000313|Proteomes:UP000019377};
RX   PubMed=24356824; DOI=10.1128/genomea.00920-13;
RA   Oliveira J.V.D.C., dos Santos R.A.C., Borges T.A., Riano-Pachon D.M.,
RA   Goldman G.H.;
RT   "Draft genome sequence of Pseudozyma brasiliensis sp. nov. strain GHG001, a
RT   high producer of endo-1,4-xylanase isolated from an insect pest of
RT   sugarcane.";
RL   Genome Announc. 1:E0092013-E0092013(2013).
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DR   EMBL; KI545860; EST08177.1; -; Genomic_DNA.
DR   RefSeq; XP_016293166.1; XM_016435433.1.
DR   STRING; 1365824.V5GQG5; -.
DR   GeneID; 27418053; -.
DR   eggNOG; KOG2128; Eukaryota.
DR   HOGENOM; CLU_000972_1_0_1; -.
DR   OMA; KGVLVHW; -.
DR   OrthoDB; 12619at2759; -.
DR   Proteomes; UP000019377; Unassembled WGS sequence.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   CDD; cd21206; CH_IQGAP; 1.
DR   CDD; cd05127; RasGAP_IQGAP_like; 1.
DR   Gene3D; 1.20.5.190; -; 1.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR000593; RasGAP_C.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR14149:SF14; PATTERNED EXPRESSION SITE; 1.
DR   PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR   Pfam; PF00307; CH; 1.
DR   Pfam; PF00612; IQ; 2.
DR   Pfam; PF00616; RasGAP; 1.
DR   Pfam; PF03836; RasGAP_C; 1.
DR   SMART; SM00033; CH; 1.
DR   SMART; SM00015; IQ; 9.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF143885; RGC domain-like; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS50096; IQ; 7.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019377}.
FT   DOMAIN          245..352
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          936..1164
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          1..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          109..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          810..837
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        48..84
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1600 AA;  179607 MW;  975DAAF5AE508D02 CRC64;
     MPPASRDNLF NSSTVGRARA YSPTKDSDRS VSPSKNGSYD SPLASPKKED SSWITSPSTP
     KQGSFWSNGT NGANGGSNTV GPSQLHLGGV RDLKRSSVGA LKMMQGFTQK TDDMGSPGDQ
     PGHTRMTVGR SRGQRTHSID ATGGPLSDRL NSLNLEPTIE EGWQKPGRPG RMESEDQEGE
     IVLPGITTGA EDVAGLQGRI RLARADGPGT MALGRPATAT SNLPMTSSSK WMDTQRHLLQ
     AYEYLCHCGE AKEWMELHVG EHLGDVVEME NEMRNGIFLA KLAKQFEPDC VPRIFVHPKL
     QYRHTDNINY FFSFINKVGL PHFFQFELTD LYEKKNFPKI VYCIHALSHV LARQGRARKV
     GNLIGKLEFT DDQLQKTQKG LDASGVAMPS FGGVGKALAK EMNMEPEPEP ETEQERIDRE
     LMENIDSVVA LQTVSRAFVS RSRFADRVEA EIQRRHEEEA RLAAAAEAER VRQRRAEEDR
     IVSRWTPLMQ AQIRGVLARR THHRKHAAVH TSTRTYVGLQ AAVRAKLARQ THVEHVKRVH
     DTGNAQAIEN FQACARGALY RRRFFENIKA LDKHENDVVG LQAQIRGRLA RVAYDNLIYR
     LADSTEDVIG LQAACRTVLA KQKLLGTIRG LRNSNDAITA VQAQIRGVLA RKNHVRMRSA
     LQKVEVKAAV GGLQSFARAA LARRKHQEQK KQLDFVTPDV VGIQAAIRGM LVRTEYDWWR
     AHIIQSEPVA IHLQSLIRGA LSRRKFFSRL RHYHEHMDKV VKIQSLFRGR QQGEQYRSLT
     MGTNVPVATI KNFGHLLNDS DADFEDEIEV ERLRKLVVRA IRESQTLEND VSELDTKIAL
     LVKNKIGIEE LIKAKNERGL LGQRDAAAAV QKRNSLLVAA NDPFADHALD RSSRRKFELY
     QELFYALQTR PEYLARLFAR VGKIDMADQD KRQVEKIVLT LFGYAQKARE EFLLLKLFQR
     CVEEELGFVS TVQEFIRGNA QFIKLVAQYN RGARERKYLK DLLSPLVQDV MSQDGLDLET
     DPCAIYRSTI TQEEMETGQP SRRPLEVAFN EALADPMART IFIRHLQSLR ATTEAFLSAI
     LSSTRKMPYG VRYIAREVFR ALQAKFPNEP EDALIKVVGH LVYYRYLNPA IVAPEGFDVV
     ETLVGPMQRK NLAEVSKMLT QIAVGRLFND DNPYLQPLND YVSSASERFA KWLHGIIDCP
     DAELHFGADE FVDHTVQQKP VIYISPNEIY SMHLLLSQQV DHLAQGQDDP LRVILKELGA
     PPVSNTQELN SARDSEITFE LVSRMATLQD PEAETKALFV ETKRLVLSLL KVQSGKTLVD
     VFVAPVTDRE EQQWVEIVSH EMVTDRSRSA YAGAGRLEDV RRLTFAELKA RTLENMLQLE
     QLHKVSRANN YQDMLNAIAI DIRNKHRKRI QRTNEKTAMH ATLTTLKEKK RYLEEQIGSY
     HSYIDASMQT MQGRKGKRRF VVPFSQQWSH LRSLKANGGR VPKFGSYRYA CGKLMEKGVL
     VSVDGLGGMT SSGSGTLRGN SGAGAGGGAG EVNLTISSDQ AGVFTVEVLN GPAAGISTDL
     RIEDLLESQF NNTPTLQILD GAAEANVNLL VHLINKKFYA
//