ID V5INW5_NEUCR Unreviewed; 291 AA.
AC V5INW5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Fumarylacetoacetate hydrolase {ECO:0000313|EMBL:ESA43762.1};
GN ORFNames=NCU07506 {ECO:0000313|EMBL:ESA43762.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:ESA43762.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:ESA43762.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- SIMILARITY: Belongs to the FAH family. {ECO:0000256|ARBA:ARBA00010211}.
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DR EMBL; CM002236; ESA43762.1; -; Genomic_DNA.
DR RefSeq; XP_011393182.1; XM_011394880.1.
DR AlphaFoldDB; V5INW5; -.
DR STRING; 367110.V5INW5; -.
DR PaxDb; 5141-EFNCRP00000007383; -.
DR EnsemblFungi; ESA43762; ESA43762; NCU07506.
DR GeneID; 3881202; -.
DR VEuPathDB; FungiDB:NCU07506; -.
DR InParanoid; V5INW5; -.
DR OrthoDB; 9433at2759; -.
DR Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.90.850.10; Fumarylacetoacetase-like, C-terminal domain; 1.
DR InterPro; IPR011234; Fumarylacetoacetase-like_C.
DR InterPro; IPR036663; Fumarylacetoacetase_C_sf.
DR PANTHER; PTHR11820; ACYLPYRUVASE; 1.
DR PANTHER; PTHR11820:SF112; FUMARYLACETOACETATE HYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G02370)-RELATED; 1.
DR Pfam; PF01557; FAA_hydrolase; 1.
DR SUPFAM; SSF56529; FAH; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ESA43762.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805}.
FT DOMAIN 72..280
FT /note="Fumarylacetoacetase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01557"
SQ SEQUENCE 291 AA; 31837 MW; C3AEE6C5136C99BB CRC64;
MASFTRLVRF LARDGRTYYG DALLPQGVSD IRAAKQARLI TGDIFGSYTV TDQVADIRLL
LSPLAPEDVR TIRCLGLNYE QHAREANMPI PTFPVLFYKP VTSLSGPTDP IPISRMAQEG
EGLDYECELV AIIGKRCRDV SEDQALDYVL GYAVGNDVSH RDWQIKRGGG QWSLGKGFDG
WAPFGPGIVS KDLIKDPQTL KISTKLNGKT VQESSTADMI FSVKKTIAFL SRGTTLLPGD
VIWTGTPQGV GMGRKPQLWL KNGDVVEVEL EKVGTCKNKV EFEASGPASK L
//
