ID V5N001_FRG3V Unreviewed; 95 AA.
AC V5N001;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE RecName: Full=thymidylate synthase {ECO:0000256|ARBA:ARBA00011947};
DE EC=2.1.1.45 {ECO:0000256|ARBA:ARBA00011947};
OS Chinese giant salamander iridovirus.
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC Pimascovirales; Iridoviridae; Alphairidovirinae; Ranavirus; Frog virus 3.
OX NCBI_TaxID=1213990 {ECO:0000313|EMBL:AHA80871.1, ECO:0000313|Proteomes:UP000114904};
RN [1] {ECO:0000313|EMBL:AHA80871.1, ECO:0000313|Proteomes:UP000114904}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGSIV-HN1104 {ECO:0000313|EMBL:AHA80871.1};
RX PubMed=24906872; DOI=10.1016/j.vetmic.2014.05.009;
RA Li W., Zhang X., Weng S., Zhao G., He J., Dong C.;
RT "Virion-associated viral proteins of a Chinese giant salamander (Andrias
RT davidianus) iridovirus (genus Ranavirus) and functional study of the major
RT capsid protein (MCP).";
RL Vet. Microbiol. 172:129-139(2014).
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DR EMBL; KF512820; AHA80871.1; -; Genomic_DNA.
DR Proteomes; UP000114904; Genome.
DR GO; GO:0004799; F:thymidylate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.572.10; Thymidylate synthase/dCMP hydroxymethylase domain; 1.
DR InterPro; IPR045097; Thymidate_synth/dCMP_Mease.
DR InterPro; IPR023451; Thymidate_synth/dCMP_Mease_dom.
DR InterPro; IPR036926; Thymidate_synth/dCMP_Mease_sf.
DR InterPro; IPR000398; Thymidylate_synthase.
DR NCBIfam; TIGR03284; thym_sym; 1.
DR PANTHER; PTHR11548:SF2; THYMIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11548; THYMIDYLATE SYNTHASE 1; 1.
DR Pfam; PF00303; Thymidylat_synt; 1.
DR SUPFAM; SSF55831; Thymidylate synthase/dCMP hydroxymethylase; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..95
FT /note="Thymidylate synthase/dCMP hydroxymethylase"
FT /evidence="ECO:0000259|Pfam:PF00303"
SQ SEQUENCE 95 AA; 10812 MW; 7187FE0A0783D1FC CRC64;
MGLGVPFNIA SYSLLTYMMA HVTGLEPGEF VHTLGDAHVY LDHVEPLKTQ LEREPIPFPT
LRINRRVESL DDFKAEDFSL EGYDPHPAIR MRMAV
//
