ID V5N451_ICTPU Unreviewed; 143 AA.
AC V5N451;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Hemoglobin alpha 2 {ECO:0000313|EMBL:AHA82584.1};
DE SubName: Full=Hemoglobin subunit alpha {ECO:0000313|RefSeq:XP_017309928.1};
GN Name=LOC108257040 {ECO:0000313|RefSeq:XP_017309928.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:AHA82584.1};
RN [1] {ECO:0000313|EMBL:AHA82584.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24334243; DOI=10.1016/j.cbd.2013.11.002;
RA Feng J., Liu S., Wang X., Wang R., Zhang J., Jiang Y., Li C.,
RA Kaltenboeck L., Li J., Liu Z.;
RT "Channel catfish hemoglobin genes: identification, phylogenetic and
RT syntenic analysis, and specific induction in response to heat stress.";
RL Comp. Biochem. Physiol. Part D Genomics Proteomics 9:11-22(2014).
RN [2] {ECO:0000313|RefSeq:XP_017309928.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_017309928.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the globin family.
CC {ECO:0000256|ARBA:ARBA00008705, ECO:0000256|PROSITE-ProRule:PRU00238,
CC ECO:0000256|RuleBase:RU000356}.
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DR EMBL; KF471102; AHA82584.1; -; mRNA.
DR RefSeq; XP_017309928.1; XM_017454439.2.
DR STRING; 7998.ENSIPUP00000015273; -.
DR Ensembl; ENSIPUT00000015915; ENSIPUP00000015273; ENSIPUG00000010371.
DR GeneID; 108257040; -.
DR KEGG; ipu:108257040; -.
DR OMA; RIMAFIN; -.
DR OrthoDB; 2939502at2759; -.
DR Proteomes; UP000221080; Chromosome 24.
DR GO; GO:0005833; C:hemoglobin complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR CDD; cd08927; Hb-alpha-like; 1.
DR Gene3D; 1.10.490.10; Globins; 1.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR012292; Globin/Proto.
DR InterPro; IPR002338; Hemoglobin_a-typ.
DR InterPro; IPR002339; Hemoglobin_pi.
DR PANTHER; PTHR11442; HEMOGLOBIN FAMILY MEMBER; 1.
DR PANTHER; PTHR11442:SF48; HEMOGLOBIN SUBUNIT ALPHA; 1.
DR Pfam; PF00042; Globin; 1.
DR PRINTS; PR00612; ALPHAHAEM.
DR PRINTS; PR00815; PIHAEM.
DR SUPFAM; SSF46458; Globin-like; 1.
DR PROSITE; PS01033; GLOBIN; 1.
PE 2: Evidence at transcript level;
KW Heme {ECO:0000256|RuleBase:RU000356}; Iron {ECO:0000256|RuleBase:RU000356};
KW Metal-binding {ECO:0000256|RuleBase:RU000356};
KW Oxygen transport {ECO:0000256|ARBA:ARBA00022621,
KW ECO:0000256|RuleBase:RU000356}; Transport {ECO:0000256|RuleBase:RU000356}.
FT DOMAIN 3..143
FT /note="Globin family profile"
FT /evidence="ECO:0000259|PROSITE:PS01033"
SQ SEQUENCE 143 AA; 15832 MW; 403365E31E0E0A1A CRC64;
MSLSAKDKAV VKDLWAKIAP KADKIGAEAL GRLFEVYPQT KTYFSHWSDL TPGSPQVKKH
GGVIVRKIGE AVGHIDDLTG ALSSLSELHA FKLRVDPVNF KLLSHTIEVS IALFFPAEFT
PEVHVSFDKF LQNLALALSE KYR
//
