ID V5RJ48_SPIAP Unreviewed; 327 AA.
AC V5RJ48;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=Phosphate acetyltransferase {ECO:0000256|ARBA:ARBA00021528};
DE EC=2.3.1.8 {ECO:0000256|ARBA:ARBA00012707};
DE AltName: Full=Phosphotransacetylase {ECO:0000256|ARBA:ARBA00031108};
GN Name=eutD {ECO:0000313|EMBL:AHB36732.1};
GN ORFNames=SAPIS_v1c08870 {ECO:0000313|EMBL:AHB36732.1};
OS Spiroplasma apis B31.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC Spiroplasma.
OX NCBI_TaxID=1276258 {ECO:0000313|EMBL:AHB36732.1, ECO:0000313|Proteomes:UP000018550};
RN [1] {ECO:0000313|EMBL:AHB36732.1, ECO:0000313|Proteomes:UP000018550}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B31 {ECO:0000313|EMBL:AHB36732.1};
RX PubMed=24407648;
RA Ku C., Lo W.S., Chen L.L., Kuo C.H.;
RT "Complete Genome Sequence of Spiroplasma apis B31T (ATCC 33834), a
RT Bacterium Associated with May Disease of Honeybees (Apis mellifera).";
RL Genome Announc. 2:e01151-13(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + phosphate = acetyl phosphate + CoA;
CC Xref=Rhea:RHEA:19521, ChEBI:CHEBI:22191, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.8;
CC Evidence={ECO:0000256|ARBA:ARBA00000705};
CC -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis;
CC acetyl-CoA from acetate: step 2/2. {ECO:0000256|ARBA:ARBA00004989}.
CC -!- SIMILARITY: Belongs to the phosphate acetyltransferase and
CC butyryltransferase family. {ECO:0000256|ARBA:ARBA00005656}.
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DR EMBL; CP006682; AHB36732.1; -; Genomic_DNA.
DR RefSeq; WP_023790108.1; NC_022998.1.
DR AlphaFoldDB; V5RJ48; -.
DR STRING; 1276258.SAPIS_v1c08870; -.
DR KEGG; sapi:SAPIS_v1c08870; -.
DR PATRIC; fig|1276258.3.peg.909; -.
DR eggNOG; COG0280; Bacteria.
DR HOGENOM; CLU_019723_0_1_14; -.
DR OrthoDB; 9805787at2; -.
DR Proteomes; UP000018550; Chromosome.
DR GO; GO:0016407; F:acetyltransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.10950; -; 1.
DR Gene3D; 3.40.50.10750; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR InterPro; IPR012147; P_Ac_Bu_trans.
DR InterPro; IPR004614; P_AcTrfase.
DR InterPro; IPR042113; P_AcTrfase_dom1.
DR InterPro; IPR042112; P_AcTrfase_dom2.
DR InterPro; IPR002505; PTA_PTB.
DR NCBIfam; TIGR00651; pta; 1.
DR PANTHER; PTHR43356; PHOSPHATE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43356:SF3; PHOSPHATE ACETYLTRANSFERASE; 1.
DR Pfam; PF01515; PTA_PTB; 1.
DR PIRSF; PIRSF000428; P_Ac_trans; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000018550};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 11..315
FT /note="Phosphate acetyl/butaryl transferase"
FT /evidence="ECO:0000259|Pfam:PF01515"
SQ SEQUENCE 327 AA; 36384 MW; ABD6D5D2E50B379D CRC64;
MYSISDLNVL IKKNKNKKTI VFPEGTETEI VQVANKIIEE ELANVILLYD NKNEIPSTLN
SKIKTYIVGE VDKSMVNLLM EIRKGKITEE EALNLVTKRN YFGALLVKLG EADCMVCGLS
YTTADTLRPT LQIIKTSDSY SIASSVLILS KDEEQIIFTD CALNVDPSPR QLAEISVMAA
NFAKDMNVKD VQVSLLSYST NSSGSGQMVE KVKEAVNILN EKTNNDFIFD GEMQFDSAYV
KKVRDKKYSC SKITKEKPDV MVFPDLNSGN IGYKIAQRMG GYKASGPFIL GLNKPVNDLS
RGATFQDIYE TSIVTLFQAL QRNGEIN
//
