GenomeNet

Database: UniProt
Entry: V5WKS3_9SPIO
LinkDB: V5WKS3_9SPIO
Original site: V5WKS3_9SPIO 
ID   V5WKS3_9SPIO            Unreviewed;       336 AA.
AC   V5WKS3;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   28-FEB-2018, entry version 24.
DE   SubName: Full=D-lactate dehydrogenase {ECO:0000313|EMBL:AHC16245.1};
DE            EC=1.1.1.28 {ECO:0000313|EMBL:AHC16245.1};
GN   ORFNames=L21SP2_2897 {ECO:0000313|EMBL:AHC16245.1};
OS   Salinispira pacifica.
OC   Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Salinispira.
OX   NCBI_TaxID=1307761 {ECO:0000313|EMBL:AHC16245.1, ECO:0000313|Proteomes:UP000018680};
RN   [1] {ECO:0000313|EMBL:AHC16245.1, ECO:0000313|Proteomes:UP000018680}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L21-RPul-D2 {ECO:0000313|EMBL:AHC16245.1,
RC   ECO:0000313|Proteomes:UP000018680};
RX   PubMed=26203324; DOI=10.1186/1944-3277-10-7;
RA   Ben Hania W., Joseph M., Schumann P., Bunk B., Fiebig A., Sproer C.,
RA   Klenk H.P., Fardeau M.L., Spring S.;
RT   "Complete genome sequence and description of Salinispira pacifica gen.
RT   nov., sp. nov., a novel spirochaete isolated form a hypersaline
RT   microbial mat.";
RL   Stand. Genomic Sci. 10:7-7(2015).
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP006939; AHC16245.1; -; Genomic_DNA.
DR   RefSeq; WP_024269142.1; NC_023035.1.
DR   ProteinModelPortal; V5WKS3; -.
DR   EnsemblBacteria; AHC16245; AHC16245; L21SP2_2897.
DR   KEGG; slr:L21SP2_2897; -.
DR   PATRIC; fig|1307761.3.peg.2887; -.
DR   KO; K03778; -.
DR   OrthoDB; POG091H04R6; -.
DR   BioCyc; SSP1307761:G1HMC-2758-MONOMER; -.
DR   Proteomes; UP000018680; Chromosome.
DR   GO; GO:0008720; F:D-lactate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR029753; D-isomer_DH_CS.
DR   InterPro; IPR029752; D-isomer_DH_CS1.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
DR   PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018680};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003719,
KW   ECO:0000313|EMBL:AHC16245.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018680}.
FT   DOMAIN       23    328       2-Hacid_dh. {ECO:0000259|Pfam:PF00389}.
FT   DOMAIN      110    297       2-Hacid_dh_C. {ECO:0000259|Pfam:PF02826}.
FT   COILED      301    321       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   336 AA;  37252 MW;  A74CE6F2777726B6 CRC64;
     MKIAVFSTKN WVRQSFDGAN EAGSFQFTYL EARLDMNTVS LAAGHDAVCV FVNDVLDAPV
     IKELKNLGVE TIALRCAGFN NVDLKTAHEE GLHVVRVPAY SPYAIAEHAL GLILALNRRY
     HRAYNRIREG NFALDGLLGF DIHGKTIGVI GTGKIGQIFC RMMKGFNCRI LAYDKYPNDE
     LKAEGVEYTS LEKLYEQSDI ISLHCPLTHE TYHIINEYAI KSMKSGVTVI NTSRGPLIDS
     NAVINGLKSG QIGYLGLDVY EEEGDLFFED LSDQVIQDDT FVRLQTFPNV LITAHQAFFT
     KEAVDNIAET TLNNLKEIEE KGESGNSVVP EQAYGG
//
DBGET integrated database retrieval system