ID V5X8G4_MYCNE Unreviewed; 790 AA.
AC V5X8G4;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Pyruvate water dikinase {ECO:0000313|EMBL:AHC24745.1};
GN ORFNames=D174_09200 {ECO:0000313|EMBL:AHC24745.1};
OS Mycolicibacterium neoaurum VKM Ac-1815D.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=700508 {ECO:0000313|EMBL:AHC24745.1, ECO:0000313|Proteomes:UP000018763};
RN [1] {ECO:0000313|EMBL:AHC24745.1, ECO:0000313|Proteomes:UP000018763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-1815D {ECO:0000313|EMBL:AHC24745.1,
RC ECO:0000313|Proteomes:UP000018763};
RX PubMed=24435872;
RA Shtratnikova V.Y., Bragin E.Y., Dovbnya D.V., Pekov Y.A., Schelkunov M.I.,
RA Strizhov N., Ivashina T.V., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum
RT Strain VKM Ac-1815D.";
RL Genome Announc. 2:e01177-13(2014).
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DR EMBL; CP006936; AHC24745.1; -; Genomic_DNA.
DR AlphaFoldDB; V5X8G4; -.
DR KEGG; mne:D174_09200; -.
DR eggNOG; COG0574; Bacteria.
DR eggNOG; COG3848; Bacteria.
DR Proteomes; UP000018763; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 2.
DR Gene3D; 3.50.30.10; Phosphohistidine domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR008279; PEP-util_enz_mobile_dom.
DR InterPro; IPR036637; Phosphohistidine_dom_sf.
DR InterPro; IPR002192; PPDK_AMP/ATP-bd.
DR PANTHER; PTHR43615; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR43615:SF1; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR Pfam; PF00391; PEP-utilizers; 1.
DR Pfam; PF01326; PPDK_N; 2.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52009; Phosphohistidine domain; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AHC24745.1};
KW Pyruvate {ECO:0000313|EMBL:AHC24745.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018763};
KW Transferase {ECO:0000313|EMBL:AHC24745.1}.
FT DOMAIN 47..182
FT /note="Pyruvate phosphate dikinase AMP/ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF01326"
FT DOMAIN 192..242
FT /note="Pyruvate phosphate dikinase AMP/ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF01326"
FT DOMAIN 713..784
FT /note="PEP-utilising enzyme mobile"
FT /evidence="ECO:0000259|Pfam:PF00391"
SQ SEQUENCE 790 AA; 84858 MW; 566B3C65AC4CB68E CRC64;
MTSPIVEFDD ITDDSLGGKA AGLAELRRIG LAVPVGFVLA DAAQRDTIVD AVGRFTQMAS
AGAVPVAVRS SALGEDGVEQ SFAGQYETVL NVGSVDEFVA AVRRCTESVG TQRASAYSGH
DEATMHLVVQ QMVDARAAGV VFTADPTTGR RDLMIIDSVA GLGEALVDGS ASSDHLVLDA
DGTIALSECA GTPILSTAEI TAIRTGALQA ARHWGMPMDL EWAIDRAGTL WWLQARPITT
LPGDLNEMDS PVAGDDHVYT RCNIGEMMPG AFCPLTASVS GYAIDFAMQT TQVVARAQPR
YEMPWLQVGY FYGHMFLNLT EGTALSSGIL GNSREQFSMS ICGRVIDELE AKPAQPFIRK
LGNTIRLVSH ALSVGPAIRR LDDRIARFRI PATTDAREML RALESGVELY CDVTLIHVRS
SSRAAVAANM LESTLIGRAV RQGRTETDGR AEAMRLMAGA DDVESALMLQ QLRSVVATLA
DDQPEAQRFL AHAPDVAVRN LCADSAGSGL REFLGRHGHR GYRELCMRDP SWADDPAGLG
SMMQAMLRAS LVSSERVPAP ETVHDKPKKP IELLARLARG GARGREQTKA KMALMAHALK
RGYRGLGELL QRTGRLPDAD LVFFFDRSEL AQVVGDDDIT ELVRRAAKRR DALPYQDALE
FDDVSVGRPR PRIATPHAGE LGDDDTVIGR PASRGVVEGT VRVAKSVHDA GAVRPGEILV
APVTDVGWTP YFTVIAALVT DIGSSVSHGA VVAREYGLPC VVNTLIGTQT FQTGDRIRVD
GDRGLVTRIR
//
