ID   V5XEU2_MYCNE            Unreviewed;       491 AA.
AC   V5XEU2;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:AHC25934.1};
DE            EC=2.3.1.9 {ECO:0000313|EMBL:AHC25934.1};
GN   ORFNames=D174_15660 {ECO:0000313|EMBL:AHC25934.1};
OS   Mycolicibacterium neoaurum VKM Ac-1815D.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=700508 {ECO:0000313|EMBL:AHC25934.1, ECO:0000313|Proteomes:UP000018763};
RN   [1] {ECO:0000313|EMBL:AHC25934.1, ECO:0000313|Proteomes:UP000018763}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM Ac-1815D {ECO:0000313|EMBL:AHC25934.1,
RC   ECO:0000313|Proteomes:UP000018763};
RX   PubMed=24435872;
RA   Shtratnikova V.Y., Bragin E.Y., Dovbnya D.V., Pekov Y.A., Schelkunov M.I.,
RA   Strizhov N., Ivashina T.V., Ashapkin V.V., Donova M.V.;
RT   "Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum
RT   Strain VKM Ac-1815D.";
RL   Genome Announc. 2:e01177-13(2014).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC       {ECO:0000256|ARBA:ARBA00010982}.
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DR   EMBL; CP006936; AHC25934.1; -; Genomic_DNA.
DR   RefSeq; WP_019510011.1; NC_023036.2.
DR   AlphaFoldDB; V5XEU2; -.
DR   KEGG; mne:D174_15660; -.
DR   eggNOG; COG0183; Bacteria.
DR   HOGENOM; CLU_026848_1_0_11; -.
DR   Proteomes; UP000018763; Chromosome.
DR   GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR   Gene3D; 2.40.50.840; -; 1.
DR   Gene3D; 3.40.47.10; -; 1.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR040771; TLP1_add_C.
DR   PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR18919:SF139; THIOLASE-LIKE PROTEIN TYPE 1 ADDITIONAL C-TERMINAL DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF18313; TLP1_add_C; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000313|EMBL:AHC25934.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018763};
KW   Transferase {ECO:0000313|EMBL:AHC25934.1}.
FT   DOMAIN          406..487
FT                   /note="Thiolase-like protein type 1 additional C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18313"
SQ   SEQUENCE   491 AA;  53161 MW;  6D1799E6E797B45A CRC64;
     MTIDPRTPVL VGFGQTNQRE ESATTEPVDL MEAAARAAAD PRVLAAVDSV RIVNLLSWRY
     RDPGLLLAQR IGAASAATRY TPIGGNVPQS LVNQACLDIQ QGRNDVVLIS GGETWRSRTR
     LRARGEKLTG TKQDESVPLA PGSDEEFALA GPGELRIHLD RPSFVYPMFE QALRIAAGAA
     PVEHQRRIGE LWSRFSAVAA TNPHAWNREP LSAEEIANPG PKNRMISTPY TKLMNSNNMV
     DQGAALILMS AEKATYLQIP TERWVFPYAG TDAHDTYEIS HRAEFHGSPA IRIGGLTALE
     LAQTDLADIA LVDVYSCFPS AVQVAANELG LALDDPRRPL TVTGGLTFAG GPWNNYVTHS
     IATMAERLIA EPGSRGLITA NGGYLTKHSF GVYGTEPPSH EFRWEDVQQK VDAEPTRAAE
     VEWSGVGTVE TWTTPFDREG EPEKAFLAVR TPADTRTLAV LTDRSEARAS VDEDIAGAKV
     TVRADGTATL G
//