ID V5XF05_MYCNE Unreviewed; 339 AA.
AC V5XF05;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:AHC26577.1};
GN ORFNames=D174_19270 {ECO:0000313|EMBL:AHC26577.1};
OS Mycolicibacterium neoaurum VKM Ac-1815D.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=700508 {ECO:0000313|EMBL:AHC26577.1, ECO:0000313|Proteomes:UP000018763};
RN [1] {ECO:0000313|EMBL:AHC26577.1, ECO:0000313|Proteomes:UP000018763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-1815D {ECO:0000313|EMBL:AHC26577.1,
RC ECO:0000313|Proteomes:UP000018763};
RX PubMed=24435872;
RA Shtratnikova V.Y., Bragin E.Y., Dovbnya D.V., Pekov Y.A., Schelkunov M.I.,
RA Strizhov N., Ivashina T.V., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum
RT Strain VKM Ac-1815D.";
RL Genome Announc. 2:e01177-13(2014).
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP006936; AHC26577.1; -; Genomic_DNA.
DR RefSeq; WP_019513213.1; NC_023036.2.
DR AlphaFoldDB; V5XF05; -.
DR KEGG; mne:D174_19270; -.
DR eggNOG; COG0673; Bacteria.
DR HOGENOM; CLU_023194_0_2_11; -.
DR Proteomes; UP000018763; Chromosome.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42840:SF3; BINDING ROSSMANN FOLD OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10240)-RELATED; 1.
DR PANTHER; PTHR42840; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000018763}.
FT DOMAIN 4..119
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 131..329
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
SQ SEQUENCE 339 AA; 35176 MW; 0C917B8100161E99 CRC64;
MTTIGVIGLG RIGAFHTETL AGLDGIDGLV ITDERPDVTA AVAAKHGATA VGSVEELLAS
GVDGVVVAAA TPAHADLTLA AVERGIPTFC EKPIASTAAE SARVAETIMC TGVPVQVGYQ
RRFDAAFAAA KTAVDNGSLG ILHTVRSTTM DPAPPPLDYI KGSGGIFRDC AVHDFDVVRW
ITGQQAVEVY ATGSVQGDPL FAEYGDVDTA AVVVRFDGGA LGVISNARYN ARGYDCRLEI
HGFDDSVAAG WDQGAPLRNV DPANEFPTGP AHNFFMDRFT EAFRTELAGF LEVAKGGPVR
GATVADAVEV AWMAEAATES LRRGTPVALE SVKAKVGTA
//
