ID V5XF36_MYCNE Unreviewed; 465 AA.
AC V5XF36;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Cytosine permease {ECO:0000313|EMBL:AHC26617.1};
GN ORFNames=D174_19540 {ECO:0000313|EMBL:AHC26617.1};
OS Mycolicibacterium neoaurum VKM Ac-1815D.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=700508 {ECO:0000313|EMBL:AHC26617.1, ECO:0000313|Proteomes:UP000018763};
RN [1] {ECO:0000313|EMBL:AHC26617.1, ECO:0000313|Proteomes:UP000018763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-1815D {ECO:0000313|EMBL:AHC26617.1,
RC ECO:0000313|Proteomes:UP000018763};
RX PubMed=24435872;
RA Shtratnikova V.Y., Bragin E.Y., Dovbnya D.V., Pekov Y.A., Schelkunov M.I.,
RA Strizhov N., Ivashina T.V., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum
RT Strain VKM Ac-1815D.";
RL Genome Announc. 2:e01177-13(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974, ECO:0000256|PIRNR:PIRNR002744}.
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DR EMBL; CP006936; AHC26617.1; -; Genomic_DNA.
DR RefSeq; WP_019512161.1; NC_023036.2.
DR AlphaFoldDB; V5XF36; -.
DR KEGG; mne:D174_19540; -.
DR eggNOG; COG1457; Bacteria.
DR HOGENOM; CLU_026016_3_2_11; -.
DR Proteomes; UP000018763; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR026030; Pur-cyt_permease_Fcy2/21/22.
DR PANTHER; PTHR31806; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR PANTHER; PTHR31806:SF1; PURINE-CYTOSINE PERMEASE FCY2-RELATED; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
DR PIRSF; PIRSF002744; Pur-cyt_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR002744};
KW Reference proteome {ECO:0000313|Proteomes:UP000018763};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR002744}.
FT TRANSMEM 40..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..417
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 465 AA; 48576 MW; 26666743B0D89110 CRC64;
MTAAEPTTDG SYRDRIVAVE PGGNEFIAEA DRHGRPSQLL WTWASPNLEF ATIFLGVLAV
SYFGMTFWQA VAGIVVGAGL GAVAHFFLSA RGPQLGVPQM VIGRLSFGYR GNAVPSTLMA
ITAGVGWFAT NSISAAFALA TLFGIAPVWA LVLVVIVQTA LAFFGHNLVQ AFERWAFPVL
AVIFAITAVV IMSKADLGAP AVEGGVGGIG GFLLTVGATF GYVAGWTPYA ADFSRYLPST
VSPVRTGLLA ASGLFLASSV LAIVGAASVT IVTNASSDNP ADVFTSSLPG ALAAATLLAI
AIGAVAANAI NVYSAGMAFV TTGVKLPVHI ARATATVFFG IAGFLVAWWA LADAAASYEA
FLLLIAYWVG PWLGVVFADQ YLRRGQRVDG FLYDHSYSNW PGLLSFLIGL VVSFLLFCNQ
ELFVGFVVRA VPDLGDIGFF VGFLLAAGSY LVLCRAKIAA ERVPA
//
