ID   V5XFY8_MYCNE            Unreviewed;       961 AA.
AC   V5XFY8;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=4-aminobutyrate aminotransferase {ECO:0000313|EMBL:AHC26942.1};
GN   ORFNames=D174_21330 {ECO:0000313|EMBL:AHC26942.1};
OS   Mycolicibacterium neoaurum VKM Ac-1815D.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=700508 {ECO:0000313|EMBL:AHC26942.1, ECO:0000313|Proteomes:UP000018763};
RN   [1] {ECO:0000313|EMBL:AHC26942.1, ECO:0000313|Proteomes:UP000018763}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM Ac-1815D {ECO:0000313|EMBL:AHC26942.1,
RC   ECO:0000313|Proteomes:UP000018763};
RX   PubMed=24435872;
RA   Shtratnikova V.Y., Bragin E.Y., Dovbnya D.V., Pekov Y.A., Schelkunov M.I.,
RA   Strizhov N., Ivashina T.V., Ashapkin V.V., Donova M.V.;
RT   "Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum
RT   Strain VKM Ac-1815D.";
RL   Genome Announc. 2:e01177-13(2014).
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00008954}.
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DR   EMBL; CP006936; AHC26942.1; -; Genomic_DNA.
DR   RefSeq; WP_019511859.1; NC_023036.2.
DR   AlphaFoldDB; V5XFY8; -.
DR   KEGG; mne:D174_21330; -.
DR   eggNOG; COG0160; Bacteria.
DR   eggNOG; COG2334; Bacteria.
DR   HOGENOM; CLU_010757_1_2_11; -.
DR   Proteomes; UP000018763; Chromosome.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR002575; Aminoglycoside_PTrfase.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR45688; ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR45688:SF3; ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL; 1.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   Pfam; PF01636; APH; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:AHC26942.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018763};
KW   Transferase {ECO:0000313|EMBL:AHC26942.1}.
FT   DOMAIN          46..263
FT                   /note="Aminoglycoside phosphotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF01636"
SQ   SEQUENCE   961 AA;  102923 MW;  8DDF2ACE92A2506C CRC64;
     MTSAGAGCSG FNFLEQPALP APQLTEDQAT ELLATHYALR KTVRSLGSQQ DCNFTVIEED
     VPVAVLKIAN PAFTEAELVA QDVAAALIAH AEPDLRVAVP LDTTDGQKFA VADPDSGAGQ
     IRLLPYLSGG TLNARGYLSP AVVAALGDIA GRVSVALADF THPGLDRILQ WDLRYGGCVV
     DELITHVADR RDEVASAAHE AWERISAVAD ELPQQAVHLD LTDANVIAGP SGIPDGVIDF
     GDLSRSWAVS EIAITLSSVL GHPGADATSI LPGVKAFHAI RPLRPAEARA LWPLLVLRTA
     VLIVSGAQQG VLDPDNSYIT EQSEDEWRMF DTATSVPTDV MTALILSELG LAEPPVRPEI
     DNRLIADLDP DTVVTLDLSD TLDDADELAA EAVRAGGALV LTRFGKPRLG LAPLLSPDSP
     QVVETGISLW SATTIRVLAP WDGEVIDRTD DRITLRGIDF ELTLTGMGSS AAPGHMRAGE
     HLGVLGADRW TQLAVRPAGA PVAPAFCTAE LAPGWLALSC DPRTVLGLEP LHEPPQRDLL
     DRRDDSFASV QERYYRNPPR IERGHRHYLM STAGRIYLDM VNNVAVLGHA HPRVADAASR
     QLRRLNTNSR FNYEAVVEFS ERIAATLPEQ LDTVFLVNSG SEASDLAIRL AMAVTGRRDV
     VAVREAYHGW TYATDAVSTS TADNPNALST RPDWVHTVES PNSFRGKYRG AQAYRYAEEA
     VAQIEQMTAA GRPPAGFICE PVYGNAGGMA LPDGYLEQVY GAVRAAGGVA IADEVQVGYG
     RLGQWFWGFP QQQVVPDIVS VAKATGNGYP LGAVITTRAI AEGFRSQGYF FSSTGGSPLS
     CAIGLAVLDT LRDEGLQENA LRTGGYLKSR LEALAAKHPI IGTVHGMGLY LGVEMVRDPV
     TLEPATEETM AICERMLELG VVIQPTGDHQ NILKTKPPLC IDTAGADFYV DMLDRALTEL
     S
//