ID   V5XH78_MYCNE            Unreviewed;       926 AA.
AC   V5XH78;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=Oxidoreductase {ECO:0000313|EMBL:AHC26754.1};
GN   ORFNames=D174_20340 {ECO:0000313|EMBL:AHC26754.1};
OS   Mycolicibacterium neoaurum VKM Ac-1815D.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=700508 {ECO:0000313|EMBL:AHC26754.1, ECO:0000313|Proteomes:UP000018763};
RN   [1] {ECO:0000313|EMBL:AHC26754.1, ECO:0000313|Proteomes:UP000018763}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM Ac-1815D {ECO:0000313|EMBL:AHC26754.1,
RC   ECO:0000313|Proteomes:UP000018763};
RX   PubMed=24435872;
RA   Shtratnikova V.Y., Bragin E.Y., Dovbnya D.V., Pekov Y.A., Schelkunov M.I.,
RA   Strizhov N., Ivashina T.V., Ashapkin V.V., Donova M.V.;
RT   "Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum
RT   Strain VKM Ac-1815D.";
RL   Genome Announc. 2:e01177-13(2014).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR   EMBL; CP006936; AHC26754.1; -; Genomic_DNA.
DR   AlphaFoldDB; V5XH78; -.
DR   KEGG; mne:D174_20340; -.
DR   eggNOG; COG0247; Bacteria.
DR   eggNOG; COG0277; Bacteria.
DR   Proteomes; UP000018763; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.465.10; -; 1.
DR   Gene3D; 3.30.70.2740; -; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR004017; Cys_rich_dom.
DR   InterPro; IPR004113; FAD-bd_oxidored_4_C.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   PANTHER; PTHR11748:SF119; D-2-HYDROXYGLUTARATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR11748; D-LACTATE DEHYDROGENASE; 1.
DR   Pfam; PF02754; CCG; 1.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF13183; Fer4_8; 1.
DR   SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF55103; FAD-linked oxidases, C-terminal domain; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018763}.
FT   DOMAIN          26..242
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
FT   DOMAIN          578..608
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   926 AA;  97797 MW;  89D4C97418ECB120 CRC64;
     MRAAGIADVR VDGTSRALYS SDASLYRVTP QAVVFPAHPD EVAAALSVCR DRGVPLTARG
     AGTSIAGNAV GPGVVLDFSR HLNKVVSVDP ESRIAVVQPG VVQAALQRAA APHRLRFGPD
     PSSHTRCTIG GMIGNNACGS RALGYGRTSD NIAGLRVLTA AGDELVLGPG QSTSPALDEL
     AAITRAGLST IRTQFGRFGR QVSGYALENL LPENTFDVAR LMAGSEGTLA VLTEATVRLV
     GEPAHRMLVV LGYPDIATAG DATPAILEHR PTACEGIDSR IVDIVRERKG PRAVPPLPGG
     AAWVFVEVVG DTHAEVEQRA ARVGTSCAAT DFLVVDHPVQ AAALWRIRED GAGLSARSVR
     DRPAHAGWED AAVPPERLGA YLRDFDALLT EFDVTGMPYG HFGDGCMHVR IDLPLDRPGG
     TAVFREFLLA AADLVVGYGG SLSGEHGDGR ARSELLDKMY SPEALALQAA VKRAFDPGNL
     LNPGVIVDPA PLDADLRIPA APLVRQKLAL AYRHDGGNFT QAVHRCTGVG KCRADNTGTG
     GVMCPSYLAT REEKDSTRGR ARVLQEMING TDVRGGWRAP EVHAALDLCL SCKGCASDCP
     TGVDMGSYKS EVLYQSYRGR LRPASHYSLG WLPRWAALAR IAPGVVNTAA RWGGRAGLAA
     AGVDHRRHIP AFAPRSFRSW FAANVPADAP GDEVVLFVDT FTDHFTPEVG VATVRVLQDA
     GYSPRLTRRR QCCGLTWIST GQLDTARRVL GRTVAALRPF ADRGVPVVGM EPSCTAVLRA
     DAAELLDSPA AATVAGATRT LAELLTARGW APPSMQGSRV VAQPHCHHHS VMGWADDAAL
     LTTAGAEVVR LGGCCGLAGN FGVEKGHYEV SVAVAEQQLL PAVRAADPNT AVLADGYSCR
     TQLSDLSDRR GLHLAQLLAA RLPDRP
//