ID   V6ARB0_9ARCH            Unreviewed;       315 AA.
AC   V6ARB0;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Alcohol dehydrogenase GroES domain protein {ECO:0000313|EMBL:CDI05162.1};
GN   ORFNames=NITUZ_140237 {ECO:0000313|EMBL:CDI05162.1};
OS   Candidatus Nitrosotenuis uzonensis.
OC   Archaea; Nitrososphaerota; Nitrosotenuis.
OX   NCBI_TaxID=1407055 {ECO:0000313|EMBL:CDI05162.1, ECO:0000313|Proteomes:UP000018159};
RN   [1] {ECO:0000313|EMBL:CDI05162.1, ECO:0000313|Proteomes:UP000018159}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N4 {ECO:0000313|EMBL:CDI05162.1,
RC   ECO:0000313|Proteomes:UP000018159};
RX   DOI=10.1371/journal.pone.0080835;
RA   Lebedeva E.V., Hatzenpichler R., Pelletier E., Schuster N., Hauzmayer S.,
RA   Bulaev A., Grigor'eva N.V., Galushko A., Schmid M., Palatinszky M.,
RA   Le Paslier D., Daims H., Wagner M.;
RT   "Enrichment and Genome Sequence of the Group I.1a Ammonia-Oxidizing
RT   Archaeon ?Ca. Nitrosotenuis uzonensis? Representing a Clade Globally.";
RL   PLoS ONE 0:0-0(2013).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDI05162.1}.
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DR   EMBL; CBTY010000006; CDI05162.1; -; Genomic_DNA.
DR   RefSeq; WP_048194599.1; NZ_CBTY010000006.1.
DR   AlphaFoldDB; V6ARB0; -.
DR   STRING; 1407055.NITUZ_140237; -.
DR   OrthoDB; 9358at2157; -.
DR   Proteomes; UP000018159; Unassembled WGS sequence.
DR   CDD; cd08242; MDR_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43350; NAD-DEPENDENT ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR43350:SF2; PKS_ER DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          22..122
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          167..273
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   315 AA;  34860 MW;  26369A8D06559269 CRC64;
     MKVLYFEQKI TLKDDYPQPK SGEALVRVRL AGICGTDLEM IRGYMDYTGV LGHEFVGVVE
     KSNNYDLVGK RVVGEINAGC GRCTYCSSGL ERHCPQRTVL GIYKRDGAFA QYLSLPEKNL
     HTIPDSISDE EAVFIEPLAA AFEIEEQIRI QENQKIAIVG DGRLAQLIVR VLKIKNKNIT
     CFGRHQNKLH MLQKMQIAAK MGISKDDEHT FDVVVEATGN ESGFSDAIKL AKPRGTIILK
     STLASKGNLD FAPAIINEIT MVGSRCGPFR PAIEALASGV VKVNDMVSAV YPIEEFEKAF
     EEAKKPTNIK ILLRP
//