ID V6IFI7_9LEPT Unreviewed; 712 AA.
AC V6IFI7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN ORFNames=LEP1GSC062_0986 {ECO:0000313|EMBL:EQA63393.1};
OS Leptospira alexanderi serovar Manhao 3 str. L 60.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1049759 {ECO:0000313|EMBL:EQA63393.1, ECO:0000313|Proteomes:UP000018747};
RN [1] {ECO:0000313|EMBL:EQA63393.1, ECO:0000313|Proteomes:UP000018747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L 60 {ECO:0000313|EMBL:EQA63393.1,
RC ECO:0000313|Proteomes:UP000018747};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Hartskeerl R.A., Ahmed A.,
RA van der Linden H., Goris M.G.A., Vinetz J.M., Sutton G.G., Nierman W.C.,
RA Fouts D.E.;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EQA63393.1}.
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DR EMBL; AHMT02000018; EQA63393.1; -; Genomic_DNA.
DR RefSeq; WP_020983770.1; NZ_AHMT02000018.1.
DR AlphaFoldDB; V6IFI7; -.
DR STRING; 100053.GCA_002009845_00807; -.
DR OrthoDB; 9766299at2; -.
DR Proteomes; UP000018747; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF13632; Glyco_trans_2_3; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EQA63393.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 551..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 579..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 621..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 342..564
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF13632"
SQ SEQUENCE 712 AA; 82604 MW; BC18FFA6E6EF48C4 CRC64;
MKNNRYYRNQ IWITKIFLLL TIVACSFAGF EMFGIFWEQL LDHRPFAAIG QVAFFFIIAL
LTYGNFVYQF TRIGYFKRLL KHSPLSRAEL EKIYKQDCPP LAVLVPSYKE ELDVVRETLL
SAALQDYPNR RVVLLIDDPP KPKSYADFEA LQNMRALPNS LQKEFNEAAY PFIQARKEYL
ERKLSHKSKP LKETERLIQL YKDATFWFQN RVNSYDDPAI QKELPEHIRA FMRDFFFKEW
GILHLERVSE LELLWVKGGA DPERIEKEYN RLASLFCVNF STFERKKYLN LSHLPNKAMN
LNSYIALLGK RWKEREDSHG LFLEESNNAD FSFEIPEADL LITLDADSVL LPDYILKLSH
VMSSPENEKI AVVQAPYSSF PGALNVLENM AGATTDIQYQ IHQGFTYFKA TFWVGANAML
RYKALLDIRT VYEERGFQIH KYIQDNTVIE DTESSIDLLD VNWNLYNYPE RLAYSATPPD
FGSLLIQRRR WANGGLIILP KLLRYVFRRP WSLIKFIEAF FRVHYLGSIA AVNISLVILM
GSPLGEGMET YWIAVSSLPY FILYGMDLAR IGYKWIDLIQ VYSLNLLLIP VNLAGVFMSI
NQAITGKQIP FSRTPKVIGR TAIPALYVVA EYSLLAQLLF GFITNYLHRN WVYSIYNLGN
AFLLGYGIIK FIGLRFCWED ILLSMNKPPV EIVEKVAHLV EPRVTIDLEG EP
//
