ID V6JQA8_STRRC Unreviewed; 743 AA.
AC V6JQA8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Molybdopterin-binding oxidoreductase {ECO:0000313|EMBL:EST21903.1};
GN ORFNames=M878_35915 {ECO:0000313|EMBL:EST21903.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST21903.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST21903.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST21903.1};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST21903.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWQX01000314; EST21903.1; -; Genomic_DNA.
DR RefSeq; WP_023551856.1; NZ_CM002285.1.
DR AlphaFoldDB; V6JQA8; -.
DR STRING; 1352936.M878_35915; -.
DR PATRIC; fig|1352936.5.peg.7467; -.
DR HOGENOM; CLU_000422_13_3_11; -.
DR OrthoDB; 7376058at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02782; MopB_CT_1; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF14; POSSIBLE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984}.
FT DOMAIN 2..58
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 743 AA; 78744 MW; 9929DABCCC2AC14E CRC64;
MSRTALRICP LCEATCGLTL TLEGTRVTGA RGDREDVFSK GFICPKGASF AAVDSDPDRL
RTPLVRRDGE LREATWAEAF DAVAAGLRPV VEGRGPDSVG VVLGNPNVHT VAGALYPPVL
LAGLRTRSLF TASTVDQMPK HVSSGLLFGD ANAIPVPDLD HTDHLLLIGA NPLESNGSLC
TAPDFPGKLK ALKARGGHLT VVDPRRTRTA KLADRHLAIR PGTDALLLAA MAHTLFAEDL
ADPAHLAPHV QGIDELREAM EDFTPEAVSE ACDLDADVIR TLARELAAAP TAAVYARIGS
CTVPHGTLAS WLVDVLNILT GNLDRPGGAL FPQAATDKTP RPAGPGRGFT LGRWHSRVRQ
LPEAKGELPL SALAEEIDTA TAEGEPVRAL IVVAANPVLS APDGDRLDKA LDSLDFMVSV
DPYLNETSRH ADVVLPPPPP SQSPHHDFAF NTLAVRNQVR YTRPAVPLEP GRMAESEILA
RLILAATGMH GADPAAVDAM VIDQTLGKAV QEKHSPVFGR DPRELVAQLT GETGPERRLD
LMLRLGPYGD GFGARPDGLT LAKLLAHPHG IDLGPLRPRL PQPLKTRSGK AELLPEPIAA
DLPRLREALR ERPEGIVLVG RRHLRSNNSW MHNVPALTGG SNRCTLHIHP EDAARLGVRD
GADVRVKGAG GEVVAPAEVT DAVRPGVVSL PHGWGHDRPG TRLGHATEAP GVNVNQLLDG
SLLDPLSGNA VLNGVPVQLA ASL
//
