ID   V6JU50_STRRC            Unreviewed;       528 AA.
AC   V6JU50;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Cholesterol oxidase {ECO:0000313|EMBL:EST23362.1};
GN   ORFNames=M878_33430 {ECO:0000313|EMBL:EST23362.1};
OS   Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST23362.1, ECO:0000313|Proteomes:UP000017984};
RN   [1] {ECO:0000313|EMBL:EST23362.1, ECO:0000313|Proteomes:UP000017984}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DS 12.976 {ECO:0000313|EMBL:EST23362.1,
RC   ECO:0000313|Proteomes:UP000017984};
RX   PubMed=24407645;
RA   Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT   "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT   12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL   Genome Announc. 2:e01147-e01113(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EST23362.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AWQX01000286; EST23362.1; -; Genomic_DNA.
DR   RefSeq; WP_023551376.1; NZ_CM002285.1.
DR   AlphaFoldDB; V6JU50; -.
DR   STRING; 1352936.M878_33430; -.
DR   PATRIC; fig|1352936.5.peg.6964; -.
DR   HOGENOM; CLU_040036_0_0_11; -.
DR   OrthoDB; 3587784at2; -.
DR   Proteomes; UP000017984; Chromosome.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR47470; CHOLESTEROL OXIDASE; 1.
DR   PANTHER; PTHR47470:SF1; FAD-DEPENDENT OXIDOREDUCTASE 2 FAD BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017984}.
FT   DOMAIN          465..516
FT                   /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05199"
SQ   SEQUENCE   528 AA;  56598 MW;  F7DA920EF2B6644F CRC64;
     MAALQTAAAL GFTRIGLQSA RAAQPDAVES APAIVIGSGY GGAVAALRLG QAGIRTVVLE
     MGRLWNTAGG DGKVFCSTSA PDQRSMWFRT RTEAPLAAFL WLDVVNKDIS PYPGVLDRVH
     YDDMSVYVGR GVGGGSLVNG GMAVTPLKSY FTEQFPTVDA DEMYGTYYPR ARAMLGVNTI
     DPAWFESTDW YRFTRTSRKA AGNAGLRTTF VPNVYDFGYM QQEAAGTATR SALAGEVIYG
     NNYGKRSLDK TYWAAALGTG NVTIHTLEKV KAVTRADDGS YVLTADRIDT TGAIVETKQY
     SCTYLFLGGG SLGTTELLVR ARDTGTLSDL NSAVGAGWGT NGNTMLGRAN HVWDTVGANE
     ATMPVMGIDD WANTDNPVFA EIAPLPMGFE HWISLYLAIT KNPERASFTY DSASGAVKLG
     WSAAQSAVSV SMAKKLFDRI NLANATIYRY DLFGPTSKVF ADDFTYHPLG GCVLGKATDD
     YGRVKGYDRL YVTDGSLVPG NIGVNPFVTI TALAERTMAR VLAEDTAP
//