ID V6JW46_STRNV Unreviewed; 331 AA.
AC V6JW46;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Cation diffusion facilitator family transporter {ECO:0000313|EMBL:EST24077.1};
GN ORFNames=M877_25865 {ECO:0000313|EMBL:EST24077.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST24077.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST24077.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST24077.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST24077.1}.
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DR EMBL; AWQW01000180; EST24077.1; -; Genomic_DNA.
DR RefSeq; WP_023541330.1; NZ_CM002280.1.
DR AlphaFoldDB; V6JW46; -.
DR STRING; 193462.BBN63_21665; -.
DR PATRIC; fig|1352941.4.peg.5270; -.
DR eggNOG; COG0053; Bacteria.
DR HOGENOM; CLU_021126_0_1_11; -.
DR OrthoDB; 9806522at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:InterPro.
DR Gene3D; 1.20.1510.10; Cation efflux protein transmembrane domain; 1.
DR InterPro; IPR002524; Cation_efflux.
DR InterPro; IPR036837; Cation_efflux_CTD_sf.
DR InterPro; IPR027469; Cation_efflux_TMD_sf.
DR InterPro; IPR040177; SLC30A9.
DR NCBIfam; TIGR01297; CDF; 1.
DR PANTHER; PTHR13414; HUEL-CATION TRANSPORTER; 1.
DR PANTHER; PTHR13414:SF9; ZINC TRANSPORTER 9; 1.
DR Pfam; PF01545; Cation_efflux; 1.
DR SUPFAM; SSF160240; Cation efflux protein cytoplasmic domain-like; 1.
DR SUPFAM; SSF161111; Cation efflux protein transmembrane domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 308..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 331 AA; 34789 MW; 1E565E211F861F6A CRC64;
MSASGGTKAI VAALAANLAI AVAKFVAFLF SGSSSMLAES VHSLADSGNQ GLLLLGGKRA
KREATPEHPF GYGRERYIYA FLVSIVLFSV GGMFAIYEGY EKIKHPHAIE AWYWPVGVLV
FAIIVESISF RTAIVESNAT RGKRSWKEFI RHSKAPELPV VLLEDLGALV GLVLALVGVS
LALGTGNGVW DGIGTLCIGV LLIVIAIVLA AETKSLLLGE AAGLEDVEKI KAAMVDGDVV
TGIIHMRTLH LGPEELLVAA KIAVEHDDTA AEVAHAINAA ETRIREAVPI ARVIYLEPDI
YSAAAAATGT NPAKSPGATE TEPVTEADTD N
//
