ID V6K3K8_STRRC Unreviewed; 294 AA.
AC V6K3K8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Short-chain dehydrogenase {ECO:0000313|EMBL:EST26687.1};
GN ORFNames=M878_26660 {ECO:0000313|EMBL:EST26687.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST26687.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST26687.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST26687.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484, ECO:0000256|RuleBase:RU000363}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST26687.1}.
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DR EMBL; AWQX01000221; EST26687.1; -; Genomic_DNA.
DR RefSeq; WP_023549887.1; NZ_CM002285.1.
DR AlphaFoldDB; V6K3K8; -.
DR STRING; 1352936.M878_26660; -.
DR PATRIC; fig|1352936.5.peg.5567; -.
DR HOGENOM; CLU_010194_2_1_11; -.
DR OrthoDB; 3743899at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR44196; DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B; 1.
DR PANTHER; PTHR44196:SF5; POSSIBLE MULTI-FUNCTIONAL ENZYME WITH ACYL-COA-REDUCTASE ACTIVITY ACRA1; 1.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SMART; SM00822; PKS_KR; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984}.
SQ SEQUENCE 294 AA; 31723 MW; 112CA72AB364B394 CRC64;
MSRVSLEGQV AVVTGAARGV GELLARKLSA RGAKVALVGL EEEALKEVSS RLHSDSAYWY
ADVTDHETMS RIAREVKARF GKVDIVVANA GVASGGPFVD SDPQAWRRVI EVNLIGSAVT
ARAFLPVLTE SRGYLLQIAS LAAITPAPMM TAYCASKSGV EAYAHCLRAE VGYQGVRVGV
GYLSWTDTDM VRGADQDDVM RELRQRLPWP SNKTYPLGPA VDRLVAGIER RSAHVYGQWW
LRGMQGVRGY LPGIIGTVGQ REMKRFAPRL QGMRSGLVGA GGAADEAARA THRN
//
