ID   V6K421_STRNV            Unreviewed;       550 AA.
AC   V6K421;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:EST26798.1};
GN   ORFNames=M877_18475 {ECO:0000313|EMBL:EST26798.1};
OS   Streptomyces niveus NCIMB 11891.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST26798.1, ECO:0000313|Proteomes:UP000017971};
RN   [1] {ECO:0000313|EMBL:EST26798.1, ECO:0000313|Proteomes:UP000017971}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST26798.1,
RC   ECO:0000313|Proteomes:UP000017971};
RX   PubMed=24407644;
RA   Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT   "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT   Aminocoumarin Antibiotic Novobiocin.";
RL   Genome Announc. 2:e01146-e01113(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EST26798.1}.
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DR   EMBL; AWQW01000129; EST26798.1; -; Genomic_DNA.
DR   RefSeq; WP_023539911.1; NZ_CM002280.1.
DR   AlphaFoldDB; V6K421; -.
DR   STRING; 193462.BBN63_15575; -.
DR   PATRIC; fig|1352941.4.peg.3771; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_000445_43_8_11; -.
DR   OrthoDB; 118142at2; -.
DR   Proteomes; UP000017971; Chromosome.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
PE   4: Predicted;
FT   DOMAIN          327..546
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   550 AA;  59302 MW;  256E76A47342D5CC CRC64;
     MNEGRLLKQY EALLGAVPQS VWVLSANGVV SLLRDGGMPE RLWHPDGESS WMDAVHPKDR
     DWFQRAWRRA NQERSPLDTI VRVRLEEAPD RFRHIKIIAA PVLDGTGELE WVGTATDAED
     HWRTRMREKL LARMAPVPAA HNLSEAFLTT AAAVVPELAD AVAVFHVQGD AEAAFRPAGG
     IPAAASPERV GLAPGLPPMH PLDADFLLGP AVQEVIRSQE AGLLTFPPGG PPEDSLSRVS
     VRWLREADAT SVALLPVVVD GRTVALATTA TCRGNPPSDE ADVYLLQDVF QQMSGPLRRT
     IELQGIRDMA LVLQQSFLAV PPSVEGLAIT ALYHPADSAA EVGGDWYDAV RLSADSLALS
     IGDIAGHDLD AATAMGRVNS ILRGLAYDSG PAASPAATLS RLDRIVQALD SPSMVTAVHA
     VLHRQADNAW HIALSNAGHP PPLLIPADAP SRYLHDLTAA DPPLCVDEAL PRNDLHAVIR
     EGDTLVLYTD GLVEVPGTDI GDGLRHLREQ TDALVRKGVS QLSLIRALLP PVQNRWDDIA
     VIALQARRER
//