ID V6K5E3_STRRC Unreviewed; 529 AA.
AC V6K5E3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Methylmalonyl-CoA carboxyltransferase {ECO:0000313|EMBL:EST27263.1};
GN ORFNames=M878_25020 {ECO:0000313|EMBL:EST27263.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST27263.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST27263.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST27263.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST27263.1}.
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DR EMBL; AWQX01000214; EST27263.1; -; Genomic_DNA.
DR RefSeq; WP_023549567.1; NZ_CM002285.1.
DR AlphaFoldDB; V6K5E3; -.
DR STRING; 1352936.M878_25020; -.
DR PATRIC; fig|1352936.5.peg.5215; -.
DR HOGENOM; CLU_018822_6_2_11; -.
DR OrthoDB; 9803706at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR PANTHER; PTHR43842:SF2; BIOTIN-DEPENDENT ACETYL-_PROPIONYL-COENZYME A CARBOXYLASE BETA5 SUBUNIT; 1.
DR PANTHER; PTHR43842; PROPIONYL-COA CARBOXYLASE BETA CHAIN; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017984};
KW Transferase {ECO:0000313|EMBL:EST27263.1}.
FT DOMAIN 7..272
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 276..523
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
SQ SEQUENCE 529 AA; 56929 MW; BB838FAC890B018F CRC64;
MTILDDLTVS TAAPDLRRAA AELRRIKEEV SRGPDPEATR RQHAKNKLTA HERLAVLFDE
GTFTEIEPLR RHRATGFGLE DKKPHGDGVV IGWGLVHGRT VFAYAHDFRV FAGALGEAHA
AKVHKVMDLA EAAGAPLVSL NDGAGARIQE GVTALAGYGG IFRRNVAASG VIPQISVMLG
PCAGGAAYSP ALTDFVFMVR ETAQMFITGP DVVQAVTGEK ITHNGLGGAE PHATASGVCH
FAYDDETECL EDVRFLISLL PSNNRELPPA ASADDPADRR TEALCDLVPA EPGRSYDVRD
VIGELVDDGE YFEVHEAWAR NVVCALARLD GHTVGIVANQ PAVLAGVLDI HASEKAARFV
STCDAFNIPL VTLVDVPGFL PGVDQEHNGI IRHGAKLLYA YCNATVPRIS VVLRKAYGGA
YIVMDSRSIG CDLSFAWPTN EIAVMGAEGA ANVIFRREIN AADDPDAVRA QRIKEYKTEL
MHPYYAAERG LVDDVIEPAE TRSVLIRSLA MLRGKKAEVP ARKHGNLPT
//
