ID V6K6N3_STRNV Unreviewed; 631 AA.
AC V6K6N3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=NADH:ubiquinone oxidoreductase subunit L {ECO:0000313|EMBL:EST27835.1};
GN ORFNames=M877_15960 {ECO:0000313|EMBL:EST27835.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST27835.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST27835.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST27835.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST27835.1}.
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DR EMBL; AWQW01000116; EST27835.1; -; Genomic_DNA.
DR RefSeq; WP_023539424.1; NZ_CM002280.1.
DR AlphaFoldDB; V6K6N3; -.
DR STRING; 193462.BBN63_13370; -.
DR PATRIC; fig|1352941.4.peg.3251; -.
DR eggNOG; COG1009; Bacteria.
DR HOGENOM; CLU_007100_6_0_11; -.
DR OrthoDB; 9811798at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR Gene3D; 1.20.5.2700; -; 1.
DR InterPro; IPR018393; NADHpl_OxRdtase_5_subgr.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR003945; NU5C-like.
DR InterPro; IPR001516; Proton_antipo_N.
DR NCBIfam; TIGR01974; NDH_I_L; 1.
DR PANTHER; PTHR42829; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5; 1.
DR PANTHER; PTHR42829:SF2; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 5; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
DR PRINTS; PR01435; NPOXDRDTASE5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Ubiquinone {ECO:0000313|EMBL:EST27835.1}.
FT TRANSMEM 31..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..527
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 69..119
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 135..420
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 631 AA; 67376 MW; F62C6B6EBDF22F3C CRC64;
MENLIALLIA APLLGAGLLL CGGRRLDRVG HILGTLLAAA SFVIGVVLFA DMLGRSGDDR
ALHQHLFSWI PVESFQADIA FQLDQLSMTF VLLITGVGTL IHIYSIGYME HDERRRRFFG
YLNLFLAAML LLVLADNYLL LYFGWEGVGL ASYLLIGFWQ HKPSAATAAK KAFLVNRVGD
MGLSIAIMLM FTTFGTFAFG PVLDSTGQAS SGTITGIGLM LLLAACGKSA QVPLQSWLGD
AMEGPTPVSA LIHAATMVTA GVYLITRSGA IFNASPDAQL VVVIVGAVTL LFGAIVGCAK
DDIKKALAGS TMSQIGYMIL AAGLGPIGYV FAIMHLVTHG FFKAGLFLGA GSVMHGMNDE
VDMRKYGGLR KYMPVTFVTF GLGYLAIIGF PGLSGFWSKD KIIEAAFAKG GTEGWILGAV
TLLGAALTAY YMTRVMLMTF FGEKRWQPDA EGNQPKPHES PKSMTIPMIV LAFGSVFAGG
LFSLNESFVK WLEPVTQFEH GHPPISAAAV TTLTVVVLLI GVGVAYLQYG RKPVPVTAPR
GSLVTRAARR DLLQDDFNHV VLVRGGEHLT RSLVYVDHTL VDGVVNGTAA SFGGLSGRLR
KLQNGYARSY AVSMFGGTAV LIAATLLMRA V
//
