ID V6K7T1_STRRC Unreviewed; 419 AA.
AC V6K7T1;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Pyridine nucleotide-disulfide oxidoreductase {ECO:0008006|Google:ProtNLM};
GN ORFNames=M878_24885 {ECO:0000313|EMBL:EST27486.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST27486.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST27486.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST27486.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST27486.1}.
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DR EMBL; AWQX01000212; EST27486.1; -; Genomic_DNA.
DR RefSeq; WP_023549540.1; NZ_CM002285.1.
DR AlphaFoldDB; V6K7T1; -.
DR STRING; 1352936.M878_24885; -.
DR PATRIC; fig|1352936.5.peg.5188; -.
DR HOGENOM; CLU_003291_4_0_11; -.
DR OrthoDB; 1145at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR028202; Reductase_C.
DR PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR PANTHER; PTHR43557:SF2; RIESKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF14759; Reductase_C; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017984}.
FT DOMAIN 6..305
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 324..407
FT /note="Reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14759"
SQ SEQUENCE 419 AA; 43901 MW; 1FD8899402C61202 CRC64;
MAARGVVVIG AGQGGLDTVA TLRAKGYGGP VTLVGEEPVL PYQRPPLSKG FLTGATGHDE
LTLRTESFFA AQDIAVVRGD RAERIELDVQ RVRLASGGTL RYDKLVLATG SRPRTLPVPG
MDLSGVLTLR SLADAEALRG LLSGPPRQVV VLGAGFVGLE TAATARGLGH DVTVVEAQRR
VLARALTPQM SDWLAGRHRR QGVGLLLGAE VTALHGTPAG EVAAVQLLDG RRLPADLVIV
GVGALPETRL ATEAGLLVGD GVIVDQWLRT DDRSVYAIGD CARFPSAAHG RHIRLESVQN
ASDQARCVAA AICGESAPYT AVPWFWSEQY ALRLQMAGLT AGHDETVTVG DPDGARFSVL
CFRQGRLTGA ESVGRPADHA IARRLLSSGT GPSPAEARTP GFDLKSFVIK PSSPAPAHA
//
