ID V6KBV7_STRNV Unreviewed; 392 AA.
AC V6KBV7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Molybdopterin biosynthesis MoeZ {ECO:0000313|EMBL:EST28916.1};
GN ORFNames=M877_12860 {ECO:0000313|EMBL:EST28916.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST28916.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST28916.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST28916.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST28916.1}.
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DR EMBL; AWQW01000098; EST28916.1; -; Genomic_DNA.
DR RefSeq; WP_023538827.1; NZ_CM002280.1.
DR AlphaFoldDB; V6KBV7; -.
DR STRING; 193462.BBN63_10855; -.
DR PATRIC; fig|1352941.4.peg.2629; -.
DR eggNOG; COG0476; Bacteria.
DR eggNOG; COG0607; Bacteria.
DR HOGENOM; CLU_013325_1_1_11; -.
DR OrthoDB; 9804286at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR CDD; cd00158; RHOD; 1.
DR CDD; cd00757; ThiF_MoeB_HesA_family; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 1.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR045886; ThiF/MoeB/HesA.
DR InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR InterPro; IPR035985; Ubiquitin-activating_enz.
DR PANTHER; PTHR10953:SF102; ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3; 1.
DR PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR Pfam; PF00581; Rhodanese; 1.
DR Pfam; PF00899; ThiF; 1.
DR SMART; SM00450; RHOD; 1.
DR SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
DR PROSITE; PS50206; RHODANESE_3; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 300..390
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 392 AA; 42429 MW; 8D02D40FCDC1A5DB CRC64;
MSLPPLVEPA AELTVDEVRR YSRHLIIPDV GMDGQKRLKN AKVLVVGAGG LGSPALMYLA
AAGVGTLGIV EFDEVDESNL QRQIIHSQAD IGRSKAASAR DSVLGINPLV KVVLHEERLE
SENVMEIFAQ YDLIVDGTDN FATRYLVNDA CVLLGKPYVW GSIYRFDGQA SVFWSEHGPC
YRCLYPEPPP PGMVPSCAEG GVLGVLCASI GSIQVNEAIK LLAGIGEPLL GRLMIYDALE
MQYRQVKVRK DPDCAVCGEN PTVTELIDYE AFCGVVSEEA QVAAAGSTIT PKQLKEWLDD
GENIELIDVR EPNEFEIVSI PGAKLIPKNE FLMGNALQDL PQDKKIVLNC KTGVRSAEVL
AVLKSAGFAD AVHVGGGVVG WVNQIEPEKP IY
//
