ID V6KFP0_STRRC Unreviewed; 336 AA.
AC V6KFP0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0000313|EMBL:EST30853.1};
GN ORFNames=M878_17535 {ECO:0000313|EMBL:EST30853.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST30853.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST30853.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST30853.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST30853.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AWQX01000155; EST30853.1; -; Genomic_DNA.
DR RefSeq; WP_023547459.1; NZ_CM002285.1.
DR AlphaFoldDB; V6KFP0; -.
DR STRING; 1352936.M878_17535; -.
DR PATRIC; fig|1352936.5.peg.3679; -.
DR HOGENOM; CLU_014015_2_3_11; -.
DR OrthoDB; 4497239at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF87; OCTAPRENYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 336 AA; 35749 MW; 1E76A3A4FAF116A3 CRC64;
MTVVGPFGLS VRDQALEADV QVGLAAVEEG LLEATKSEVP FITEAAQHLV RAGGKRFRPL
LVMLAAQFGD PYAPGVVPSA VVVELTHLAT LYHDDVMDEA AVRRGVDSAN TRWGNSVAVL
TGDFLFARAS QILADLGPEA VRVQALAFER LVTGQILETA GPSDGRDPVE HYLDVLGGKT
GSLVAVSCRF GAMMSGADET VVDVLTQYGE RLGVAFQLAD DVLDIASDSH ESGKTPGTDL
REGIPTLPVL RLRERAARLG LPEDIALCEL LDSDLSDDAR HAEALAALRA HPALEQARRD
TVRYAEEARA ALAPLRECDA KAALMELCDA VVHRAG
//
