ID V6KIQ6_STRNV Unreviewed; 290 AA.
AC V6KIQ6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Transport permease protein {ECO:0000256|RuleBase:RU361157};
GN ORFNames=M877_14035 {ECO:0000313|EMBL:EST28859.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST28859.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST28859.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST28859.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU361157};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU361157}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC-2 integral membrane protein family.
CC {ECO:0000256|RuleBase:RU361157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST28859.1}.
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DR EMBL; AWQW01000099; EST28859.1; -; Genomic_DNA.
DR RefSeq; WP_023539061.1; NZ_CM002280.1.
DR AlphaFoldDB; V6KIQ6; -.
DR STRING; 193462.BBN63_11740; -.
DR PATRIC; fig|1352941.4.peg.2872; -.
DR eggNOG; COG0842; Bacteria.
DR HOGENOM; CLU_039483_2_0_11; -.
DR OrthoDB; 3370990at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR047817; ABC2_TM_bact-type.
DR InterPro; IPR000412; ABC_2_transport.
DR PANTHER; PTHR43077:SF8; DOXORUBICIN RESISTANCE ABC TRANSPORTER PERMEASE PROTEIN DRRB; 1.
DR PANTHER; PTHR43077; TRANSPORT PERMEASE YVFS-RELATED; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR PIRSF; PIRSF006648; DrrB; 1.
DR PROSITE; PS51012; ABC_TM2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU361157};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361157};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361157};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361157}; Transport {ECO:0000256|RuleBase:RU361157}.
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 83..105
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 126..154
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 160..187
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 199..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT TRANSMEM 262..281
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361157"
FT DOMAIN 43..288
FT /note="ABC transmembrane type-2"
FT /evidence="ECO:0000259|PROSITE:PS51012"
SQ SEQUENCE 290 AA; 31072 MW; 167A0F5C5AF68D57 CRC64;
MSAVTEASPK ALAPQPRGGV VQSVRDSLVV AKRNLIRMMR IPEMIIFGLI QPIMFVVLFT
YVFGGSINIP GAPSGSAQAY REFLMAGIFA QTVTFATAGA GAGIADDMHK GLIDRFRSLP
MARGAVLTGR TLADLVQTAL TLVVLAAVAL IIGWRTHENI GSVLAGFGLL LFLGYAFSWI
GALIGLIVRT PEAATSGGLI WLFPLTFISN AFVPVNGMPS FLQHVAEWNP FSATVQAARE
LFGNTIPGRE ASVTGAWPME HAVWASLIWS VLIIVVFRTL AVRRYRSATA
//
