ID V6KMK8_STRRC Unreviewed; 1078 AA.
AC V6KMK8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=OmpR/PhoB-type domain-containing protein {ECO:0000259|PROSITE:PS51755};
GN ORFNames=M878_18975 {ECO:0000313|EMBL:EST30224.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST30224.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST30224.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST30224.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST30224.1}.
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DR EMBL; AWQX01000166; EST30224.1; -; Genomic_DNA.
DR RefSeq; WP_023547739.1; NZ_CM002285.1.
DR AlphaFoldDB; V6KMK8; -.
DR STRING; 1352936.M878_18975; -.
DR PATRIC; fig|1352936.5.peg.3980; -.
DR HOGENOM; CLU_004665_2_0_11; -.
DR OrthoDB; 3862494at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000017984};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 1..106
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..106
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 260..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1078 AA; 115807 MW; 7A74D7B2009D470E CRC64;
MRRCELRFGL LGPPVLYDRP PFEISSDTPD DGVRAIGSPK VRVLLAALLL EPGRVVSVES
LKDALWGGAP PVSAQASLHN HVTRLRRLLD DPDRLRAVPP GYVLRVDHGE LDVHVFDARV
AEARAAHARR DWSGVVRACT AGLALWRGTP LSGLPADLGG YALVQRLEEA RLLLLERRYD
AELALGGARL AALVPELAAL VAEYPLREAY HRQLMLALHR TGRQAEALAV HRDLRARLIE
ELGIEPGLAV REAHVEVLRG SDEEQRRPDE ERAGLRRAVG GKVRRLPQGA GQVDGTAEEE
GEPSAPHKDA EPGPDARLTP RPAQLPAPPA HFTGRADARR ALRHALTEPP APAPAVAVIS
GMAGVGKSAL ALHVAHELRD RFTDGQLYVN LHGATPGMTP LSSAQALAAL LRDLGAEPRS
IPEHPDAAAA LLRSLLAPAR ILLVLDDAAN AAQVRPLLPA GPGCAVIVTS RSPLTALDGA
RRFPLAPLTG EDSAALLRAV SGREGLDAGH ALVELTGRLP LALRVVAARL AARRALTPDV
LAGQLAETGG RLRHLEYDDL SVRRSLAVAH DALAAAEREA DRDAALALRR IGWLDLPTYG
APLIARLTGT DERRAEAALD RLVDVALLEE TAYGRYAPHD LVRDFARELA DTGRDMGTRK
DAGAGALGAP PDAAARPGAQ PDTVHRTDSD EETTPACAAS ACDSELAALR WYAAVAERVL
EAVVEPGLDQ EDRRRATSTQ PAQHAADVTE LLSFESAEEA FAWGEVELEN VVALVARNAD
TSDRLRAAHL SVLARLLFPY VQRGGRVAEM EVLGRAALGA ARRLGDAAAE AYALGDLAGL
HFMTGRQKDA LALTDRSLEI WRRLGVVSRI RRCLNNRGLL LEGLGRFAES GEALRQSLAY
SRQLNDPYGE AVTHSHLGNL YEHTDPRAAI EQHRRSLAIG DAIGAVIVQH SAHCNIGYAH
LTLGEPAAAA GHFEKSLRIL GGHGDWHGES QTRLGLVRAL RQLGETERAG HECAELLSRA
DARADRYMGG LARHQHGLLL HARGQRAEAY DAWRAALAAL DGTDEQTIVT ELRELLTQ
//
