ID   V6KRA0_9ACTN            Unreviewed;       256 AA.
AC   V6KRA0;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=Serine aminopeptidase S33 domain-containing protein {ECO:0000259|Pfam:PF12146};
GN   ORFNames=N566_18335 {ECO:0000313|EMBL:EST34568.1};
OS   Streptomycetaceae bacterium MP113-05.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae.
OX   NCBI_TaxID=1380770 {ECO:0000313|EMBL:EST34568.1, ECO:0000313|Proteomes:UP000017915};
RN   [1] {ECO:0000313|EMBL:EST34568.1, ECO:0000313|Proteomes:UP000017915}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MP113-05 {ECO:0000313|EMBL:EST34568.1,
RC   ECO:0000313|Proteomes:UP000017915};
RA   Valde M., Degnes K.F., Sletta H., Ruckert C., Kalinowski J., Zotchev S.B.;
RT   "Streptomyces bacterium from a marine sponge: physiological
RT   characterization and genome-based analysis of secondary metabolite
RT   biosynthesis potential.";
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EST34568.1}.
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DR   EMBL; AWQV01000619; EST34568.1; -; Genomic_DNA.
DR   AlphaFoldDB; V6KRA0; -.
DR   STRING; 1380770.N566_18335; -.
DR   ESTHER; 9acto-v6kra0; CarbLipBact_2.
DR   PATRIC; fig|1380770.3.peg.3175; -.
DR   HOGENOM; CLU_076594_0_1_11; -.
DR   OrthoDB; 9786110at2; -.
DR   Proteomes; UP000017915; Unassembled WGS sequence.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR012354; Esterase_lipase.
DR   InterPro; IPR022742; Hydrolase_4.
DR   PANTHER; PTHR11614:SF121; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   PIRSF; PIRSF017388; Esterase_lipase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000017915}.
FT   DOMAIN          19..229
FT                   /note="Serine aminopeptidase S33"
FT                   /evidence="ECO:0000259|Pfam:PF12146"
FT   ACT_SITE        93
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT   ACT_SITE        194
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT   ACT_SITE        224
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR017388-1"
FT   BINDING         25
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR017388-2"
FT   BINDING         94
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR017388-2"
SQ   SEQUENCE   256 AA;  28282 MW;  3A27173DBECFDF0D CRC64;
     MPILPGAEPM RHDGSQTGVL LCHGFTGSPQ SLRPWARYLA ERGYTVSLPL LPGHGTRWED
     LQVTGWEDWY ATVERELRAL RARCSEVFVC GLSMGGALAL RLAAKHGEDV RGVIVVNPAS
     TFPRLEGYAL PVLRQLVRST RGLTDDIAKE GSHEIGYNRV PLHAAYSLRN FFRRLPSELP
     EVTQPLLLLH SRTDHVVPPG DSELILSLVS STDVTETVLE DSYHVATLDH DAERIFADTH
     GFISRISART TARDGA
//