ID V6L0R1_STRRC Unreviewed; 420 AA.
AC V6L0R1;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=von Willebrand factor type A {ECO:0000313|EMBL:EST34804.1};
GN ORFNames=M878_08790 {ECO:0000313|EMBL:EST34804.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST34804.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST34804.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST34804.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST34804.1}.
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DR EMBL; AWQX01000068; EST34804.1; -; Genomic_DNA.
DR RefSeq; WP_023545743.1; NZ_CM002285.1.
DR AlphaFoldDB; V6L0R1; -.
DR STRING; 1352936.M878_08790; -.
DR PATRIC; fig|1352936.5.peg.1879; -.
DR HOGENOM; CLU_647068_0_0_11; -.
DR OrthoDB; 4318225at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..420
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004748659"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..228
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 420 AA; 44183 MW; D4FB31443F32925C CRC64;
MITRQRLAAG VCALLAALAA GIAFPGGAVA DETQTAAPKV ELVLDVSGSM RTRDIDGGSR
MAAAKQAFDE VLDATPQEVQ LGIRTLGANY PGNDRKEGCK DTAQLYPVGT LNRTDAKTAV
ATLQPTGWTP IGPALLKAAD DLNSGGGTRR IVLITDGEDT CQPLDPCEVA REIAAKGVGL
TIDTLGLVPD AKTRDQLSCI ADATGGTYTD VRHKEQLSSR VGQLVDRAAD PVVTPVATEG
AAQCEKAPTL KSGLYTDREE FGQQRWYKVD VDPGKELRAS VSVADDRAVG PDYGVLLRAM
TVHGREIVRG EAAGTGRTDV ISTGLRYPKA ASDDDNAPAE TVCLQVTNSF AAGSGVKTTP
GLPLELTVDV VDGPSGHHDV ASFGLGRGWW LLGALVLTGF LAGLLWGWLS RWRVAIWRTN
//
