ID   V6LJ89_9EUKA            Unreviewed;       217 AA.
AC   V6LJ89;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=sn-1-specific diacylglycerol lipase {ECO:0000256|ARBA:ARBA00026104};
DE            EC=3.1.1.116 {ECO:0000256|ARBA:ARBA00026104};
GN   ORFNames=SS50377_15651 {ECO:0000313|EMBL:EST44642.1};
OS   Spironucleus salmonicida.
OC   Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Hexamitinae;
OC   Spironucleus.
OX   NCBI_TaxID=348837 {ECO:0000313|EMBL:EST44642.1};
RN   [1] {ECO:0000313|EMBL:EST44642.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Xu F., Jerlstrom-Hultqvist J., Einarsson E., Astvaldsson A., Svard S.G.,
RA   Andersson J.O.;
RT   "The Genome of Spironucleus salmonicida Highlights a Fish Pathogen Adapted
RT   to Fluctuating Environments.";
RL   PLoS Genet. 0:0-0(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty
CC         acid + H(+); Xref=Rhea:RHEA:33275, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:17389, ChEBI:CHEBI:17815,
CC         ChEBI:CHEBI:28868; EC=3.1.1.116;
CC         Evidence={ECO:0000256|ARBA:ARBA00024531};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:33276;
CC         Evidence={ECO:0000256|ARBA:ARBA00024531};
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KI546115; EST44642.1; -; Genomic_DNA.
DR   AlphaFoldDB; V6LJ89; -.
DR   EnsemblProtists; EST44642; EST44642; SS50377_15651.
DR   VEuPathDB; GiardiaDB:SS50377_24763; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002921; Fungal_lipase-like.
DR   PANTHER; PTHR45792; DIACYLGLYCEROL LIPASE HOMOLOG-RELATED; 1.
DR   Pfam; PF01764; Lipase_3; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          3..128
FT                   /note="Fungal lipase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01764"
SQ   SEQUENCE   217 AA;  25246 MW;  C90801ECD8125DEA CRC64;
     MYVCISGTWH LADTVADADS QPVQMILNDQ KVYVHQGFLQ VSQFIHDQLM ILTPYLIANK
     HIDEVIFTGH SQGAAASFIL QQMFIMRFPQ LKTQCIGFGT PPFVSKGFIL NSTQPNRTYI
     NNNDCISRAG ILYQYINEIR KAYPGFQTEQ YSEFVEENYG YDDDFYTPGD IYWLKDNNIV
     PITRYGVFIQ VDSFLNFKDH RLEYYIENIK KQISNIK
//