ID V6M390_9BACL Unreviewed; 462 AA.
AC V6M390;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Phosphohydrolase {ECO:0000313|EMBL:EST53081.1};
GN ORFNames=T458_19540 {ECO:0000313|EMBL:EST53081.1};
OS Brevibacillus panacihumi W25.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=1408254 {ECO:0000313|EMBL:EST53081.1, ECO:0000313|Proteomes:UP000017973};
RN [1] {ECO:0000313|EMBL:EST53081.1, ECO:0000313|Proteomes:UP000017973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W25 {ECO:0000313|EMBL:EST53081.1,
RC ECO:0000313|Proteomes:UP000017973};
RX PubMed=24459276;
RA Wang X., Jin D., Zhou L., Wu L., An W., Chen Y., Zhao L.;
RT "Draft Genome Sequence of Brevibacillus panacihumi Strain W25, a
RT Halotolerant Hydrocarbon-Degrading Bacterium.";
RL Genome Announc. 2:e01215-13(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST53081.1}.
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DR EMBL; AYJU01000017; EST53081.1; -; Genomic_DNA.
DR RefSeq; WP_023557722.1; NZ_KI629785.1.
DR AlphaFoldDB; V6M390; -.
DR STRING; 1408254.T458_19540; -.
DR PATRIC; fig|1408254.3.peg.3829; -.
DR eggNOG; COG3437; Bacteria.
DR HOGENOM; CLU_591440_0_0_9; -.
DR OrthoDB; 9759601at2; -.
DR Proteomes; UP000017973; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR033480; sCache_2.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF17200; sCache_2; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000313|EMBL:EST53081.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017973};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 234..438
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT DOMAIN 256..387
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 462 AA; 52405 MW; FC4DC30EE6F80DD3 CRC64;
MPLKPTTRSH LFSLFIVFLP ILFTVVVFLG YTQAKIVFYR SGVDAMDRQL GTVTQLLDLY
NEQIKHDRLS FTQVENKIRE MFVGSRHADN SSDQSRDRLA IAPGSELFVF NSQGTLIIHH
SLEGQNIFGL SQMGNGFFAK KVLFEGMDTV SYSFSEPGSP SHSSSIATIR YYPQWDWYIT
LTMDEEAFYQ QFSQVKSFLI MIVTVSYLIT AILFYRTYHK EKAFVSSKLQ SVQLAEVNQS
ILKTLAVALE ERDAYTSGHS QRVAYYMRII GKQMGLDDET LDMMYTGGLL HDIGKIGIED
NILLKKGRLT EEEAEVIKSH TVRGEALLRK LYAQAASKDA SRIKKILMIT RHHHERYDGT
GYPDQLKEEN IPLLARVAAV ADSFDAMTSS RAYRKALSFS KACDEIIQNA GTQFCPKVVD
AFFQSVTEDT FHHAHHISRA NELLEPIVKE TEVIYTQHPI GG
//
