ID V6M641_9BACL Unreviewed; 297 AA.
AC V6M641;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:EST53365.1};
GN ORFNames=T458_21320 {ECO:0000313|EMBL:EST53365.1};
OS Brevibacillus panacihumi W25.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=1408254 {ECO:0000313|EMBL:EST53365.1, ECO:0000313|Proteomes:UP000017973};
RN [1] {ECO:0000313|EMBL:EST53365.1, ECO:0000313|Proteomes:UP000017973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W25 {ECO:0000313|EMBL:EST53365.1,
RC ECO:0000313|Proteomes:UP000017973};
RX PubMed=24459276;
RA Wang X., Jin D., Zhou L., Wu L., An W., Chen Y., Zhao L.;
RT "Draft Genome Sequence of Brevibacillus panacihumi Strain W25, a
RT Halotolerant Hydrocarbon-Degrading Bacterium.";
RL Genome Announc. 2:e01215-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST53365.1}.
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DR EMBL; AYJU01000017; EST53365.1; -; Genomic_DNA.
DR RefSeq; WP_023558053.1; NZ_KI629785.1.
DR AlphaFoldDB; V6M641; -.
DR STRING; 1408254.T458_21320; -.
DR PATRIC; fig|1408254.3.peg.4184; -.
DR eggNOG; COG2084; Bacteria.
DR HOGENOM; CLU_035117_1_0_9; -.
DR OrthoDB; 9786703at2; -.
DR Proteomes; UP000017973; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR015815; HIBADH-related.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43060; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR43060:SF15; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-LIKE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PIRSF; PIRSF000103; HIBADH; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000017973}.
FT DOMAIN 10..167
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 171..291
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT ACT_SITE 177
FT /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ SEQUENCE 297 AA; 31669 MW; 4ED255CC7125CD6D CRC64;
MEAHTEKSVI GFVGTGVMGK SMASHFIKAG YPVLVYTRSK EKAEEILAQG AVWKERVADL
AGEANVIITM VGYPHDVEEV YLGEQGVIAH AKPGTYLIDM TTSKPSLAQR IYEEAKKHAL
HSLDAPVSGG DIGARDAKLT IMVGGDQEAF DAMAPLLGIM GTNVILQGGP GAGQHTKMCN
QITIASNMIG VCEAISYAKK AGLDPTRVLD SIGAGAAGSW SLNNLAPRMI AGNYAPGFYI
KHMIKDMSIA LESAKEMGLL TPGLELAKSL YDEMAAEGEE NSGTQALIKW YERNQRP
//
