ID   V6M8F2_9BACL            Unreviewed;       490 AA.
AC   V6M8F2;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=GGDEF domain-containing protein {ECO:0000259|PROSITE:PS50887};
GN   ORFNames=T458_11730 {ECO:0000313|EMBL:EST54532.1};
OS   Brevibacillus panacihumi W25.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=1408254 {ECO:0000313|EMBL:EST54532.1, ECO:0000313|Proteomes:UP000017973};
RN   [1] {ECO:0000313|EMBL:EST54532.1, ECO:0000313|Proteomes:UP000017973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W25 {ECO:0000313|EMBL:EST54532.1,
RC   ECO:0000313|Proteomes:UP000017973};
RX   PubMed=24459276;
RA   Wang X., Jin D., Zhou L., Wu L., An W., Chen Y., Zhao L.;
RT   "Draft Genome Sequence of Brevibacillus panacihumi Strain W25, a
RT   Halotolerant Hydrocarbon-Degrading Bacterium.";
RL   Genome Announc. 2:e01215-13(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EST54532.1}.
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DR   EMBL; AYJU01000016; EST54532.1; -; Genomic_DNA.
DR   RefSeq; WP_023556280.1; NZ_KI629782.1.
DR   AlphaFoldDB; V6M8F2; -.
DR   STRING; 1408254.T458_11730; -.
DR   PATRIC; fig|1408254.3.peg.2310; -.
DR   eggNOG; COG2199; Bacteria.
DR   HOGENOM; CLU_041006_0_0_9; -.
DR   OrthoDB; 9759607at2; -.
DR   Proteomes; UP000017973; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR   PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017973};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        301..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          357..490
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   490 AA;  56584 MW;  6D2A060C2C2E77A6 CRC64;
     MNARFRLKLT MTMIVFALTI SFSITTSDYL RMRDRAIENK QNQVKQDEQL AKYALETVEK
     AYYVFGDSIA HKMKDTSLQL LDMYEENPSF ETWDFDALKR RFSLDVYVID SNNVILYSSF
     RQDIGMDFNA CCGKLAKVLD EYRNNGEFFH DGMDLEQKTG IIKKYSYMPT PDKKYIIQLG
     YSLQEGDIFH KFNFLSTIDQ LVERSQSIYA INVLNIGGYK LGDPSAIQRK LPPERRKAFE
     KTLETGTTIE CEDLWNNEPA IYRYVHYTSE YDDGTTKNKV LEIVYHDMDL QEIQNDHRNQ
     FIIQLLIILI ITIILSSLIS RWVARPMYLA FHDSLTGLNN RAAFDERLKA AISKKHEQSA
     LLMIDLDNFK LVNDHLGHDM GDHLLQCVAL VLRKVARPMD TPIRLGGDEF VLIMPSADRA
     EAEETAQQLI DSILVSTAEE FQLDGEKVTV SIGIALFPEH GLNPDMLYKR ADQALYDSKK
     KGKNQYKFYS
//