GenomeNet

Database: UniProt
Entry: V6MC39_9BACL
LinkDB: V6MC39_9BACL
Original site: V6MC39_9BACL 
ID   V6MC39_9BACL            Unreviewed;       527 AA.
AC   V6MC39;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   18-SEP-2019, entry version 29.
DE   RecName: Full=D-3-phosphoglycerate dehydrogenase {ECO:0000256|RuleBase:RU363003};
DE            EC=1.1.1.95 {ECO:0000256|RuleBase:RU363003};
GN   ORFNames=T458_01925 {ECO:0000313|EMBL:EST56096.1};
OS   Brevibacillus panacihumi W25.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae;
OC   Brevibacillus.
OX   NCBI_TaxID=1408254 {ECO:0000313|EMBL:EST56096.1, ECO:0000313|Proteomes:UP000017973};
RN   [1] {ECO:0000313|EMBL:EST56096.1, ECO:0000313|Proteomes:UP000017973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W25 {ECO:0000313|EMBL:EST56096.1,
RC   ECO:0000313|Proteomes:UP000017973};
RX   PubMed=24459276;
RA   Wang X., Jin D., Zhou L., Wu L., An W., Chen Y., Zhao L.;
RT   "Draft Genome Sequence of Brevibacillus panacihumi Strain W25, a
RT   Halotolerant Hydrocarbon-Degrading Bacterium.";
RL   Genome Announc. 2:e01215-13(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate +
CC         H(+) + NADH; Xref=Rhea:RHEA:12641, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:18110, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945,
CC         ChEBI:CHEBI:58272; EC=1.1.1.95;
CC         Evidence={ECO:0000256|RuleBase:RU363003};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-serine biosynthesis; L-serine
CC       from 3-phospho-D-glycerate: step 1/3.
CC       {ECO:0000256|RuleBase:RU363003}.
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU363003}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EST56096.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AYJU01000001; EST56096.1; -; Genomic_DNA.
DR   RefSeq; WP_023554473.1; NZ_KI629782.1.
DR   STRING; 1408254.T458_01925; -.
DR   EnsemblBacteria; EST56096; EST56096; T458_01925.
DR   PATRIC; fig|1408254.3.peg.392; -.
DR   OrthoDB; 1638924at2; -.
DR   UniPathway; UPA00135; UER00196.
DR   Proteomes; UP000017973; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004617; F:phosphoglycerate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006564; P:L-serine biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1330.90; -; 1.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR029009; ASB_dom_sf.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR029753; D-isomer_DH_CS.
DR   InterPro; IPR029752; D-isomer_DH_CS1.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006236; PGDH.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   Pfam; PF01842; ACT; 1.
DR   SUPFAM; SSF143548; SSF143548; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR01327; PGDH; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
DR   PROSITE; PS00670; D_2_HYDROXYACID_DH_2; 1.
DR   PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU363003};
KW   Complete proteome {ECO:0000313|Proteomes:UP000017973};
KW   NAD {ECO:0000256|RuleBase:RU363003};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU363003};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017973};
KW   Serine biosynthesis {ECO:0000256|RuleBase:RU363003}.
FT   DOMAIN      455    527       ACT. {ECO:0000259|PROSITE:PS51671}.
SQ   SEQUENCE   527 AA;  56896 MW;  E97E9A284D93A5E8 CRC64;
     MYKVLITDPL SEFGIQQLLD ASDVEVVRKT NLSPSDLLEI IGDYDALLVR SQTQVTADVF
     AAGKKLKAVG RAGVGVDNID INAATQAGVP VINAPDGNTI STAEHSFAML MAVARNIPQA
     HKKLADGTWD RKSFQGVELN KKVLGIIGMG RIGSEVAKRA KAFGMTVMGY DPFMTEERAQ
     KMGVTNATVD EICRQADFIT VHTPLTKETR HIISSREFAK MKDGVRLINC ARGGIIDEKA
     LYEAITTGKV AGVALDVYEE EPPVDNPLIG LPQVVHTPHL GASTVEAQEN VAVDVSEEIL
     KVLRGQPFKN AVNLPSIPAD VMEKVQPYFT LGEKLGHFLA QVTVGSVSEI EIKYSGELTD
     VDTAPLTRTV LKGVLSFRLG EGVNYVNAPL LAKVRDITVT ERKAAQNRGF TNLLTVSLKT
     SQETRTVAGT RLNGYGARIV KIDDYAIDVA PEGYLLYIHH NDRPGVIGRV GSILGTNGVN
     IATMQVGRRD IGGDAIMMLS VDKPLTAELL DTMGELPEVK SVTQIEL
//
DBGET integrated database retrieval system