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Database: UniProt
Entry: V6RZK8_9FLAO
LinkDB: V6RZK8_9FLAO
Original site: V6RZK8_9FLAO 
ID   V6RZK8_9FLAO            Unreviewed;       479 AA.
AC   V6RZK8;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   16-JAN-2019, entry version 35.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=FCR2A7T_17440 {ECO:0000313|EMBL:ESU19589.1};
OS   Flavobacterium cauense R2A-7.
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=1341154 {ECO:0000313|EMBL:ESU19589.1, ECO:0000313|Proteomes:UP000018253};
RN   [1] {ECO:0000313|EMBL:ESU19589.1, ECO:0000313|Proteomes:UP000018253}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R2A-7 {ECO:0000313|EMBL:ESU19589.1,
RC   ECO:0000313|Proteomes:UP000018253};
RA   Lee K., Yi H., Park S., Chun J.;
RT   "Flavobacterium cauense type strain genome sequencing.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ESU19589.1}.
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DR   EMBL; AVBI01000016; ESU19589.1; -; Genomic_DNA.
DR   EnsemblBacteria; ESU19589; ESU19589; FCR2A7T_17440.
DR   PATRIC; fig|1341154.3.peg.1715; -.
DR   Proteomes; UP000018253; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000018253};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      176    312       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      387    456       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     184    191       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   479 AA;  54807 MW;  04DD673415572AC3 CRC64;
     MPEYMSTTAQ SVWENCLSFI KDNIQDQAYK TWFEPIKAVE LTDNALYIQV PSKFFYEWLE
     EHYVKLLKVA LTKELGPSAK LLYKIKMENK LGNKLPFTEQ LPSNNRSAVK TQEIDVPIQN
     KNPELKNPFV IPGIRNVKIE SQLNSNYSFD NFLEGDSNRL ARSAGMAVAN KPGGTSFNPF
     LIFGGVGLGK THLAHAIGVE IKEKYPEKTV LYISAEVFTQ QYIDSVKKNT RNDFIHFYQL
     IDVLIIDDVQ FLSGKAGTQD VFFHIFNYLH QNGKQVILTS DKAPVDMQDI EQRLLSRFKW
     GLSAEIHQPD YETRVSILKN ILYRDGVEMP DDIVEYVAKN IKSNVRELEG AIISLIAQSS
     FNHREVTIEL AKQVVEKFVK NVKREVSIDY IQKIVSDYFQ LDVETLQSKT RKRDVVQARQ
     LAMFFAKKFT KASLANIGSQ IGSRDHATVL HACKTVDNLV STDKQFKKYV DDIHKKLSL
//
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