ID V6TQ67_GIAIN Unreviewed; 560 AA.
AC V6TQ67;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Ankyrin repeat protein {ECO:0000313|EMBL:ESU40502.1};
GN ORFNames=GSB_154921 {ECO:0000313|EMBL:ESU40502.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU40502.1, ECO:0000313|Proteomes:UP000018040};
RN [1] {ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GS {ECO:0000313|Proteomes:UP000018040};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU40502.1, ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS {ECO:0000313|EMBL:ESU40502.1,
RC ECO:0000313|Proteomes:UP000018040};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU40502.1}.
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DR EMBL; AHHH01000213; ESU40502.1; -; Genomic_DNA.
DR AlphaFoldDB; V6TQ67; -.
DR EnsemblProtists; ESU40502; ESU40502; GSB_154921.
DR VEuPathDB; GiardiaDB:DHA2_150646; -.
DR VEuPathDB; GiardiaDB:GL50581_1732; -.
DR VEuPathDB; GiardiaDB:GL50803_0032778; -.
DR VEuPathDB; GiardiaDB:QR46_0106; -.
DR VEuPathDB; GiardiaDB:QR46_4885; -.
DR Proteomes; UP000018040; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR PANTHER; PTHR24120; GH07239P; 1.
DR Pfam; PF12796; Ank_2; 5.
DR SMART; SM00248; ANK; 15.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 5.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT REPEAT 87..119
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 289..321
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 412..435
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 474..497
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 505..537
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 61828 MW; 91F1CA0195C2FD63 CRC64;
MSLDRPAGRN KIDASAESAV KRPSSDGETD LMRAAARGDM DEVKRHLDER GRRDANDRTA
LIWAATNGHT EIVRVLAECE GKRKDNKGMT ALMHAAIDGH AGVVRVLVKH EAKAKDRQGH
NALYHALKSG HMEIAKIIME HDEVTDKTGT TALMRAADGN DVEMVELLIP FQKTKMATED
VGINGMKIRN STALMRAAAH GYARIVELLV KHEGGVRRVG WPALMFAAQC YLPNHRLADP
FIDHPKCVEL LMESEGSISE WTELMYAAYR GDVDSVKNNL HMKGARDIGG WTALMRAAAQ
GHEEIIELLK EEGGMQNSDH QTALMWAARN GHAGCVRLLL EKEGGMRDRK SWTGLMFAVE
NDCVEVVKIL LEKEGGMQNT KRWTGLMYAA HNNNLECARL LAEREKGVQD NHGRTALMRA
AMKGHTEIVE LLAEHEGGMK DNEGVTALMH AAESGYIKMV KILLKYEKGM MSSKGRTALM
RAAESGHTDI VQILIEHEKG VATNMGMTAL MRAAMNGHIE IVELLAEHEG GMKSNEGMTA
RMLANSYKRS SIADLLAKYE
//
