ID V6TZJ9_GIAIN Unreviewed; 592 AA.
AC V6TZJ9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=EGF-like cyst protein {ECO:0000313|EMBL:ESU44146.1};
GN ORFNames=GSB_151696 {ECO:0000313|EMBL:ESU44146.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU44146.1, ECO:0000313|Proteomes:UP000018040};
RN [1] {ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GS {ECO:0000313|Proteomes:UP000018040};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU44146.1, ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS {ECO:0000313|EMBL:ESU44146.1,
RC ECO:0000313|Proteomes:UP000018040};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU44146.1}.
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DR EMBL; AHHH01000028; ESU44146.1; -; Genomic_DNA.
DR AlphaFoldDB; V6TZJ9; -.
DR EnsemblProtists; ESU44146; ESU44146; GSB_151696.
DR VEuPathDB; GiardiaDB:DHA2_151072; -.
DR VEuPathDB; GiardiaDB:GL50581_31; -.
DR VEuPathDB; GiardiaDB:GL50803_0016322; -.
DR VEuPathDB; GiardiaDB:QR46_1160; -.
DR Proteomes; UP000018040; Unassembled WGS sequence.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR Pfam; PF07974; EGF_2; 2.
DR SMART; SM00181; EGF; 8.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 3.
PE 4: Predicted;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..592
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004752107"
FT DOMAIN 134..145
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS00022"
FT DOMAIN 237..248
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS01186"
FT DOMAIN 476..487
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS00022,
FT ECO:0000259|PROSITE:PS01186"
FT DOMAIN 576..587
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS00022,
FT ECO:0000259|PROSITE:PS01186"
SQ SEQUENCE 592 AA; 63274 MW; 3E655B3135FD6341 CRC64;
MILALLLATL CTAIKCPEGE VEVDGVCYPS SCVFDGTVCG GHGTCVDSVC QCDHGCKLGN
QGCYPSKCYL VSDDVCNGHG KCVESDQGEY ECSCDQGYIN DYGACLPEAC YTEEGLCFGY
GDCIEPTDGS APYCKCFPAN AGEKCTECSS DATFINGECV HKSCFSELIP GETLVCNGMG
RCQAIFFPDV HYVCTCYPLD ATFYNNTCVY DGCITESNPY GVMEVCSDRG ICTNTRCTCD
SGYNGPTCEY KVVDCQPGFV SAQETCYPEV CVSDDIICGG YGHCVWNDDG AACACDDGFV
FYENTCIYAS CIVNGVVCPH GTYDTEWNPP QCICPVDYII KDSVCYPSTC VTNRQTDPIQ
LCNSAGTCDF DTGACNCYLT NAGPTCSECS SDATFIDGVC QPWPCIDERD PNALSVCSGK
GTCVSETGSD PFDVFYSCVC DTGYRPIPGG ICASAKCVTT SFIICNNRGS CIDGACHCDE
GYSGTLCEWY DCPAGQTFVN NMCTPNECVT HYDDAKQTTS VCGNYGRCVK DGDSHKCSCR
SDAKVVDGEC VSEKCITNSS TNEVCSGHGK CNGYFCICSV GYSGDTCKFA TY
//
