ID V6U159_GIAIN Unreviewed; 576 AA.
AC V6U159;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE SubName: Full=CDP-diacylglycerol--serine O-phosphatidyltransferase {ECO:0000313|EMBL:ESU44706.1};
GN ORFNames=GSB_151449 {ECO:0000313|EMBL:ESU44706.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU44706.1, ECO:0000313|Proteomes:UP000018040};
RN [1] {ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GS {ECO:0000313|Proteomes:UP000018040};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU44706.1, ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS {ECO:0000313|EMBL:ESU44706.1,
RC ECO:0000313|Proteomes:UP000018040};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU44706.1}.
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DR EMBL; AHHH01000017; ESU44706.1; -; Genomic_DNA.
DR AlphaFoldDB; V6U159; -.
DR EnsemblProtists; ESU44706; ESU44706; GSB_151449.
DR VEuPathDB; GiardiaDB:DHA2_153651; -.
DR VEuPathDB; GiardiaDB:GL50581_928; -.
DR VEuPathDB; GiardiaDB:GL50803_0017427; -.
DR VEuPathDB; GiardiaDB:QR46_3889; -.
DR Proteomes; UP000018040; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1760; -; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:ESU44706.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 576 AA; 65197 MW; 1DDBAF2B1CC845E5 CRC64;
MEPKAALALL VSFILVWVAT GHGLSYLMGS QTVCNPNIMV SLCLFFGLLV SLLLYNGHTT
LALMVYIICV AASTANILNL KPRIKLAKRP KWKPWLLGTQ ARLWIMPYSE QCFYIPILFF
LMIPRLQPVS SIVQAINLQS TDEQAPYISL IDPALAMLFI ILSSWSNVAI RRQARQNTLR
SLFKHSCLYT CLFIQFLLND NKSLFYHDTN VFRILTFRRS LNVSQLEYFS NILLFFAALL
VTIEQFLSRI PQNWYANCVS ILNLFCGLLG IHFLISPPQS ATSSNLLGIL VLSCIMVGQL
FDLFDGRVAE KWGSTKNGEL FDDVADATSF GLAVGLLIRH VSRSLMSSSE GSKLRSDLWP
IIIAGIYIFC VFYRLVRFVL NKRAQCVKGG VYFFFGLPSP ATATMAGLLC VLFEQDWTFS
RVWTYNLSTS TIKQISFSVS VLILCLLTVS NIPYPHLGRV LYRRGVLPQS FRISIEALFV
VSAIYGMYYR TPLLMLYCLG SLSVLYLFTP VYADKLGWYN RDFTVKEKHK ETLFLVQQRK
VARLEQMYTN ALAKLKKINA QAPSGNKTSS EDLTSE
//
