ID V6U411_GIAIN Unreviewed; 716 AA.
AC V6U411;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Ankyrin repeat protein {ECO:0000313|EMBL:ESU45711.1};
GN ORFNames=GSB_11164 {ECO:0000313|EMBL:ESU45711.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU45711.1, ECO:0000313|Proteomes:UP000018040};
RN [1] {ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GS {ECO:0000313|Proteomes:UP000018040};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU45711.1, ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS {ECO:0000313|EMBL:ESU45711.1,
RC ECO:0000313|Proteomes:UP000018040};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU45711.1}.
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DR EMBL; AHHH01000002; ESU45711.1; -; Genomic_DNA.
DR AlphaFoldDB; V6U411; -.
DR EnsemblProtists; ESU45711; ESU45711; GSB_11164.
DR VEuPathDB; GiardiaDB:DHA2_11164; -.
DR VEuPathDB; GiardiaDB:GL50581_1033; -.
DR VEuPathDB; GiardiaDB:GL50803_0011164; -.
DR VEuPathDB; GiardiaDB:QR46_1865; -.
DR Proteomes; UP000018040; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24184:SF11; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24184; SI:CH211-189E2.2; 1.
DR Pfam; PF12796; Ank_2; 3.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 97..129
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 594..626
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 420..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 336..363
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 420..451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 716 AA; 79192 MW; 23CB921123807712 CRC64;
MRSSTTTDWF NAAFDNDHRF IRENVDTYAR TIDSTRETAL MKAARRNCGA VVEILCDQEH
GLYNSRGENA LMLAIQNNSV DCLDLLCEYE SEQMVSNGDT PLHYAVRMGC VDAISYLTSR
YKRARSRSDR TPLEFAAELG SIRSIEHLLV SGTPYTQLEI DTAIERARAC GQMVIVSTLP
ILFKRYWRVA DSRKSTGEPV TVEDLRTFEP DIASGEPIVD NLALKNALLS AGVPVNEANS
VVRSLSQPAN QSVRQHTAPV PCTDSFRELT DSMRQLAYPN QEAFSKGYEL QDGPQVATSV
YQDPGADGVD YANFMGLRGR RDDESIVSAD VVDNIVAVKN AEIARLESAL REANARLRMA
ESNAAVNRAN RINGSSPGQI DRKTHEYIPG RVESPLNYCS AKIANDGGDH RAAYRGDAYS
TSCSIQSPSR SCRSASRSKS RSSSRSTSRS HYGRNYKPEV KPRANSTLDV TRSESARTSQ
LKPELLVPPM TQRRLQPGSA GDSDLIVAVK NGDIIKFRKY LPTQTRQVDS RGRSALMHAV
DRNNTLMITE LCNIEAGIQD ADGTTALMIA AALNLPLAVS MLVSHEKRFT KRTDGSTALM
AAAANGNIDC VDILARHEKG IQAHDGSTAL IHAIRNNRRR CACMLWPFEY TIADRDGMSP
RDWAKKFNRQ EILRVVESHT PSSAEAKSNM QLVPTINSSY MVRDIEHTVN LLNTVK
//
