ID V6U5Z6_GIAIN Unreviewed; 381 AA.
AC V6U5Z6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=tRNA delta(2)-isopentenylpyrophosphate transferase {ECO:0000313|EMBL:ESU44675.1};
GN ORFNames=GSB_150135 {ECO:0000313|EMBL:ESU44675.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU44675.1, ECO:0000313|Proteomes:UP000018040};
RN [1] {ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GS {ECO:0000313|Proteomes:UP000018040};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU44675.1, ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS {ECO:0000313|EMBL:ESU44675.1,
RC ECO:0000313|Proteomes:UP000018040};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- SIMILARITY: Belongs to the IPP transferase family.
CC {ECO:0000256|ARBA:ARBA00005842}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU44675.1}.
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DR EMBL; AHHH01000018; ESU44675.1; -; Genomic_DNA.
DR AlphaFoldDB; V6U5Z6; -.
DR EnsemblProtists; ESU44675; ESU44675; GSB_150135.
DR VEuPathDB; GiardiaDB:DHA2_150613; -.
DR VEuPathDB; GiardiaDB:GL50581_4494; -.
DR VEuPathDB; GiardiaDB:GL50803_0017480; -.
DR VEuPathDB; GiardiaDB:QR46_0933; -.
DR Proteomes; UP000018040; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR039657; Dimethylallyltransferase.
DR InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR11088; TRNA DIMETHYLALLYLTRANSFERASE; 1.
DR PANTHER; PTHR11088:SF95; TRNA DIMETHYLALLYLTRANSFERASE; 1.
DR Pfam; PF01715; IPPT; 1.
DR Pfam; PF12874; zf-met; 1.
DR SMART; SM00451; ZnF_U1; 1.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ESU44675.1}.
FT DOMAIN 342..376
FT /note="U1-type"
FT /evidence="ECO:0000259|SMART:SM00451"
SQ SEQUENCE 381 AA; 42275 MW; 08CE261F8C9DF19B CRC64;
MGDMVIRPLV LLMGTTASGK TRLALQLAQT LSGEIICGDA LQLWQGIPIL SAAPTPDEQV
AVKHHLFGLY APFQKDDSSR LIYERKTVRD WYASVCDVLR EIQPPHTPII VGGTHYFFLF
FLSQPGTRDL LHSVGLQPVL LFCDAHAALA YRVADRVASM VGQGLLSEVS LLLSSLELER
ITRVTEGYVR DGVSDGIMQA IGLREFILAT QQSDAFKTFM SDESIKGLSP FDVSAHTKIL
LYSVLNDPTA RTDSIVHFAD TLSVSMEAAL QLGAVLLEVF DNTVAYAKQQ KKWVRRIERH
GLSILRIDTS TWNDNIVDLA LEEVSKASCC AGINYTFLQL SSQTLYCDAC NVVVTGQKVY
EEHIQSRAHR RKLNSKRKNT S
//
