ID   V6YZ53_STRAG            Unreviewed;       367 AA.
AC   V6YZ53;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:ESV53902.1};
GN   ORFNames=SAG0136_01215 {ECO:0000313|EMBL:ESV53902.1};
OS   Streptococcus agalactiae LMG 14747.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1154860 {ECO:0000313|EMBL:ESV53902.1, ECO:0000313|Proteomes:UP000018482};
RN   [1] {ECO:0000313|EMBL:ESV53902.1, ECO:0000313|Proteomes:UP000018482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 14747 {ECO:0000313|EMBL:ESV53902.1,
RC   ECO:0000313|Proteomes:UP000018482};
RA   Richards V.P., Durkin S.A.S., Kim M., Pavinski Bitar P.D., Stanhope M.J.,
RA   Town C.D., Venter J.C.;
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESV53902.1}.
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DR   EMBL; ANQC01000019; ESV53902.1; -; Genomic_DNA.
DR   AlphaFoldDB; V6YZ53; -.
DR   eggNOG; COG0287; Bacteria.
DR   Proteomes; UP000018482; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          3..293
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   367 AA;  40761 MW;  8D528C867738285B CRC64;
     MTKTILIAGL GLIGGSLALA IRKQHPDYHI LGYNRGEASR NIALERGMVD DASDDFKSLA
     VQADVIILCV PIQKTIDMIK DLASFELKPN VLVTDAGSTK GAIIAAAERY LADKDINFIG
     SHPMAGSHKS GAVAVDVNLF ENAYFIMTPC RLTKPDAVPR LTDLLTASGA RFVQIDAAEH
     DLVTSQISHF PHVLASSLML QAGDYALEHP FTKNFAAGGF RDMTRIAESE PGMWTSILMT
     NPKPILERIE EFKERLDRVS DLLKTGNQDA IWHFFEHGRQ TRKAMEIHKR AGVDSFFDIF
     ISIPDKEDSI LSVLEVLRGI SLVNIRINEE NRADTYGVLQ ITFKNQEDLD EAVKRLSQET
     DYIISFD
//